Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

C De Smet; C Lurquin; E De Plaen; F Brasseur; H Zarour; O De Backer; P G Coulie; T Boon

doi:10.1038/eye.1997.59

Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

C De Smet, C Lurquin, E De Plaen, F Brasseur, H Zarour, O De Backer, P G Coulie, T Boon

Namur Research Institute for Life Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

It is now well established that human melanoma cells express antigens that are recognised by cytolytic T lymphocytes derived from the tumour-bearing patient. The molecular definition of these antigens is progressing at an accelerated pace. The currently characterised melanoma antigens can be classified into three categories: differentiation antigens, antigens encoded by genes that are specifically expressed in tumours, and antigens encoded by mutated genes. Several of these antigens are sufficiently tumour-specific to qualify them as candidate anti-cancer vaccines in melanoma patients.

Original language	English
Pages (from-to)	243-8
Number of pages	6
Journal	Eye (London, England)
Volume	11 ( Pt 2)
DOIs	https://doi.org/10.1038/eye.1997.59
Publication status	Published - 1997

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10.1038/eye.1997.59

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title = "Genes coding for melanoma antigens recognised by cytolytic T lymphocytes",

abstract = "It is now well established that human melanoma cells express antigens that are recognised by cytolytic T lymphocytes derived from the tumour-bearing patient. The molecular definition of these antigens is progressing at an accelerated pace. The currently characterised melanoma antigens can be classified into three categories: differentiation antigens, antigens encoded by genes that are specifically expressed in tumours, and antigens encoded by mutated genes. Several of these antigens are sufficiently tumour-specific to qualify them as candidate anti-cancer vaccines in melanoma patients.",

author = "{De Smet}, C and C Lurquin and {De Plaen}, E and F Brasseur and H Zarour and {De Backer}, O and Coulie, {P G} and T Boon",

year = "1997",

doi = "10.1038/eye.1997.59",

language = "English",

volume = "11 ( Pt 2)",

pages = "243--8",

journal = "Eye (London, England)",

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T1 - Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

AU - De Smet, C

AU - Lurquin, C

AU - De Plaen, E

AU - Brasseur, F

AU - Zarour, H

AU - De Backer, O

AU - Coulie, P G

AU - Boon, T

PY - 1997

Y1 - 1997

N2 - It is now well established that human melanoma cells express antigens that are recognised by cytolytic T lymphocytes derived from the tumour-bearing patient. The molecular definition of these antigens is progressing at an accelerated pace. The currently characterised melanoma antigens can be classified into three categories: differentiation antigens, antigens encoded by genes that are specifically expressed in tumours, and antigens encoded by mutated genes. Several of these antigens are sufficiently tumour-specific to qualify them as candidate anti-cancer vaccines in melanoma patients.

AB - It is now well established that human melanoma cells express antigens that are recognised by cytolytic T lymphocytes derived from the tumour-bearing patient. The molecular definition of these antigens is progressing at an accelerated pace. The currently characterised melanoma antigens can be classified into three categories: differentiation antigens, antigens encoded by genes that are specifically expressed in tumours, and antigens encoded by mutated genes. Several of these antigens are sufficiently tumour-specific to qualify them as candidate anti-cancer vaccines in melanoma patients.

U2 - 10.1038/eye.1997.59

DO - 10.1038/eye.1997.59

M3 - Article

C2 - 9349420

SN - 0950-222X

VL - 11 ( Pt 2)

SP - 243

EP - 248

JO - Eye (London, England)

JF - Eye (London, England)

ER -

Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

Abstract

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