Evaluation expérimentale de la fonction pulmonaire chez le porc

This synthesis aims to review the pulmonary function tests available in swine. Two techniques are used in order to measure the variations of the mechanical properties of the respiratory system. The oesophageal balloon remains the most used technique in order to determine these properties in pigs. However, it requires a systematic anaesthesia of the animal. The impulse oscillometry specifically measures the mechanical properties of the respiratory system, by a non invasive way, but the animals have to be trained to be immobilized or sedated to perform the measurement. The whole body barometric plethysmographyallows measuring the respiratory pattern in unsedated freely moving piglets. That method allows investigating pigs for long term studies while minimizing the stress related to handling. From this point of view, it represents the less stressing technique for pigs. Finally, blood gases analysis is the easiest method to use in the field. It permits to assess respiratory function by measuring pH and blood partial pressures in oxygen and carbon dioxide.