Abstract
The synthesis of ethoxycarbonyl functionalized Tröger's base is accompanied by the formation of a considerable amount of a 3,4-dihydroquinazoline by-product. We found that both compounds can be readily isolated from reaction mixture on a preparative scale by standard crystallization from appropriate solvents.
Original language | English |
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Article number | 100339 |
Journal | Chemical Data Collections |
Volume | 25 |
DOIs | |
Publication status | Published - Feb 2020 |
Keywords
- Crystallization
- Dihydroquinazolines
- Reaction intermediate
- Separation
- Tröger's base
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Dive into the research topics of 'Ethoxycarbonyl functionalized Tröger's base alongside its congener dihydroquinazoline: A trick with crystallization'. Together they form a unique fingerprint.Equipment
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Physical Chemistry and characterization(PC2)
Johan Wouters (Manager) & Carmela Aprile (Manager)
Technological Platform Physical Chemistry and characterizationFacility/equipment: Technological Platform