Diagnostic accuracy of refractometer and Brix refractometer to assess failure of passive transfer in calves: protocol for a systematic review and meta-analysis

S. Buczinski, G. Fecteau, M. Chigerwe, J. M. Vandeweerd

Research output: Contribution to journalReview articlepeer-review

Abstract

Calves are highly dependent of colostrum (and antibody) intake because they are born agammaglobulinemic. The transfer of passive immunity in calves can be assessed directly by dosing immunoglobulin G (IgG) or by refractometry or Brix refractometry. The latter are easier to perform routinely in the field. This paper presents a protocol for a systematic review meta-analysis to assess the diagnostic accuracy of refractometry or Brix refractometry versus dosage of IgG as a reference standard test. With this review protocol we aim to be able to report refractometer and Brix refractometer accuracy in terms of sensitivity and specificity as well as to quantify the impact of any study characteristic on test accuracy.

Original languageEnglish
Pages (from-to)3-8
Number of pages6
JournalAnimal Health Research Reviews
Volume17
Issue number1
DOIs
Publication statusPublished - 1 Jun 2016

Keywords

  • antibody
  • immunoglobulin G
  • radial immunodiffusion
  • turbidimetric immunoassay

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