Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore

Nathalie Meurice; Laurence Leherte; Daniel Vercauteren; Jean-Jacques Bourguignon; Camille-Georges Wermuth

Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore

Nathalie Meurice, Laurence Leherte, Daniel Vercauteren, Jean-Jacques Bourguignon, Camille-Georges Wermuth

Unit of theoretical and structural physico-chemistry

Research output: Contribution in Book/Catalog/Report/Conference proceeding › Chapter

Original language	English
Title of host publication	Computer-Assisted Lead Finding and Optimization
Editors	H Eds., van de, B Waterbeemd, G Testa
Place of Publication	Bâle
Publisher	Verlag Helvetica Chimica Acta
Pages	497-509
Number of pages	13
Publication status	Published - 1997

1 Finished
1 Active

Multiresolution analysis of electron density maps
Leherte, L., Vercauteren, D. & Meurice, N.
1/09/95 → …
Project: Research
Study of the similarity between ligands of pharmacological interest by the development of genetic algorithm methods
Leherte, L., Vercauteren, D. & Meurice, N.
1/09/95 → 31/12/04
Project: PHD

Cite this

Meurice, N., Leherte, L., Vercauteren, D., Bourguignon, J.-J., & Wermuth, C.-G. (1997). Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore. In H. Eds., V. de, B. Waterbeemd, & G. Testa (Eds.), Computer-Assisted Lead Finding and Optimization (pp. 497-509). Verlag Helvetica Chimica Acta.

Meurice, Nathalie ; Leherte, Laurence ; Vercauteren, Daniel et al. / Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore. Computer-Assisted Lead Finding and Optimization. editor / H Eds. ; van de ; B Waterbeemd ; G Testa. Bâle : Verlag Helvetica Chimica Acta, 1997. pp. 497-509

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title = "Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore",

author = "Nathalie Meurice and Laurence Leherte and Daniel Vercauteren and Jean-Jacques Bourguignon and Camille-Georges Wermuth",

note = "Publication editors : Eds. H. van de Waterbeemd, B. Testa, G. Folkers",

year = "1997",

language = "English",

pages = "497--509",

editor = "H Eds. and van de and B Waterbeemd and G Testa",

booktitle = "Computer-Assisted Lead Finding and Optimization",

publisher = "Verlag Helvetica Chimica Acta",

}

Meurice, N, Leherte, L , Vercauteren, D, Bourguignon, J-J & Wermuth, C-G 1997, Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore. in H Eds., V de, B Waterbeemd & G Testa (eds), Computer-Assisted Lead Finding and Optimization. Verlag Helvetica Chimica Acta, Bâle, pp. 497-509.

Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore. / Meurice, Nathalie; Leherte, Laurence ; Vercauteren, Daniel et al.
Computer-Assisted Lead Finding and Optimization. ed. / H Eds.; van de; B Waterbeemd; G Testa. Bâle: Verlag Helvetica Chimica Acta, 1997. p. 497-509.

Research output: Contribution in Book/Catalog/Report/Conference proceeding › Chapter

TY - CHAP

T1 - Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore

AU - Meurice, Nathalie

AU - Leherte, Laurence

AU - Vercauteren, Daniel

AU - Bourguignon, Jean-Jacques

AU - Wermuth, Camille-Georges

N1 - Publication editors : Eds. H. van de Waterbeemd, B. Testa, G. Folkers

PY - 1997

Y1 - 1997

M3 - Chapter

SP - 497

EP - 509

BT - Computer-Assisted Lead Finding and Optimization

A2 - Eds., H

A2 - de, van

A2 - Waterbeemd, B

A2 - Testa, G

PB - Verlag Helvetica Chimica Acta

CY - Bâle

ER -

Meurice N, Leherte L , Vercauteren D, Bourguignon JJ, Wermuth CG. Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore. In Eds. H, de V, Waterbeemd B, Testa G, editors, Computer-Assisted Lead Finding and Optimization. Bâle: Verlag Helvetica Chimica Acta. 1997. p. 497-509

Development of a Genetic Algorithm Method Especially Designed for the Comparison of Molecular Models: Application to the Elucidation of the Benzodiazepine Receptor Pharmacophore

Projects

Multiresolution analysis of electron density maps

Study of the similarity between ligands of pharmacological interest by the development of genetic algorithm methods

Cite this