Deciphering the roles of ABCB5 in normal and cancer cells

Research output: Contribution to journalShort surveypeer-review


ABCB5 encodes a full transporter (ABCB5FL) and a half transporter (ABCB5β), which is unique in the ATP binding cassette (ABC) transporter superfamily. We discuss the roles of both isoforms in undifferentiated slow-cycling cells, multidrug resistance, and tumorigenesis, and their regulation pathways.

Original languageEnglish
Pages (from-to)795-798
Number of pages4
JournalTrends in Cancer
Issue number10
Publication statusPublished - Oct 2022
Externally publishedYes


  • ABCB5
  • melanocyte biology
  • melanoma


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