Chondroid metaplasia of paraspinal connective tissue in the degenerative spine

Sjoerd Stevens, Anouk Agten, Erika Wisanto, Melissa Lo Monaco, Jonas Verbrugghe, Annick Timmermans, Ivo Lambrichts, Frank Vandenabeele

Research output: Contribution to journalArticle

6 Downloads (Pure)

Abstract

A 51-year-old male was routinely biopsied during a paraspinal muscle study. The biopsy sample was taken from the right erector spinae muscle at the fourth lumbar vertebra. The patient had no history of (diagnosed) major back trauma. The obtained sample was histologically analyzed (hematoxylin and eosin, safranin O), and complementary magnetic resonance imaging was performed. The biopsied sample contained chondroid tissue. Based on its location, the biopsy sample was appointed as chondroid metaplasia. Although chondroid metaplasia is not uncommon in humans, this is the first report of chondroid metaplasia within the paraspinal connective tissue. We propose a novel mechanism to explain the paraspinal chrondrogenic changes, related to spinal degeneration.

Original languageEnglish
Pages (from-to)204-207
Number of pages4
JournalAnatomy and Cell Biology
Volume52
Issue number2
DOIs
Publication statusPublished - 1 Jun 2019

Keywords

  • Chondroid metaplasia
  • Degeneration
  • Lumbar spine
  • Muscle biopsy
  • Paraspinal

Fingerprint Dive into the research topics of 'Chondroid metaplasia of paraspinal connective tissue in the degenerative spine'. Together they form a unique fingerprint.

  • Cite this

    Stevens, S., Agten, A., Wisanto, E., Monaco, M. L., Verbrugghe, J., Timmermans, A., Lambrichts, I., & Vandenabeele, F. (2019). Chondroid metaplasia of paraspinal connective tissue in the degenerative spine. Anatomy and Cell Biology, 52(2), 204-207. https://doi.org/10.5115/acb.2019.52.2.204