Chemical constituents from Psychotria arborea Hiern (Rubiaceae)

Judith Caroline Ngo Nyobe, Willifred Dongmo Tekapi Tsopgni, Jean Pierre Longue Ekon, Ali Ben Saida, Annie Guilaine Djuidje, Anicet Biwole Bengondo, Gisele Etame Loe, Guillaume Berionni, Desire Bikele Mama, Jean Claude Ndom, Emmanuel Mpondo Mpondo

Research output: Contribution to journalArticlepeer-review


The chemical study of the stems extract of Psychotria arborea Hiern led to the isolation of thirteen compounds, including four anthraquinones: 2-methylanthracene-9,10-dione (1), 2-methoxyanthracene-9,10-dione (2), 2-hydroxy-3-methylanthracene-9,10-dione (3) and 3-hydroxy-1-methoxy-2-methylanthracene-9,10-dione (4); two diterpenes: ent-kaur-16-en-19-oic acid (5) and 15-acetoxy-ent-kaur-16-en-19-oic acid (6); two triterpenes, β-amyrin (8) and oleanolic acid (9), one flavonoid: Quercetin (7), three sterols: A mixture of stigmasterol (10) and β-sitosterol (11) and β-sitosterol-3-O-β-D-glucopyranoside (12) and one fatty acid (13). The structures of these compounds were elucidated based on NMR and HR-ESIMS analysis, further supported by comparison with previously reported spectral data. Compounds 1–4 and compounds 10–12 were tested for their antibacterial activity against three bacteria strains Escherichia coli, Staphylococcus aureus and Salmonella enterica. All these tested compounds were found to be inactive. Furthermore, the chemotaxonomic significance of the obtained compounds was discussed in detail.

Original languageEnglish
Article number104212
JournalBiochemical Systematics and Ecology
Publication statusPublished - Feb 2021


  • 2-Methylanthracene-9,10-dione
  • Anthraquinones
  • Antibacterial activities
  • Psychotria arborea
  • Rubiaceae


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