Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig

Jean-Michel Dogné; Stéphanie Rolin; Michel Pétein; Vincent Tchana-Sato; Alexandre Ghuysen; Bernard Lambermont; Julien Hanson; David Magis; Patrick Segers; Bernard Pirotte; Bernard Masereel; Pierre Drion; Vincent D'Orio; Philippe Kolh

doi:10.1016/j.thromres.2005.02.006

Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig

Jean-Michel Dogné, Stéphanie Rolin, Michel Pétein, Vincent Tchana-Sato, Alexandre Ghuysen, Bernard Lambermont, Julien Hanson, David Magis, Patrick Segers, Bernard Pirotte, Bernard Masereel, Pierre Drion, Vincent D'Orio, Philippe Kolh

Research output: Contribution to journal › Article › peer-review

Abstract

Great advances have been made in the prevention of thrombotic disorders by developments of new pharmacological and surgical treatments. Animal models of arterial thrombosis have largely contributed to the discovery and to the validation of original treatments. The purpose of the present work was to develop and validate an original model of acute myocardial infarction provoked in pig by thrombosis of the left anterior descending (LAD) coronary artery induced by topical application of ferric chloride solution.

Original language	English
Pages (from-to)	431-42
Number of pages	12
Journal	Thrombosis Research
Volume	116
Issue number	5
DOIs	https://doi.org/10.1016/j.thromres.2005.02.006
Publication status	Published - 2005

Keywords

Adenosine Triphosphate
Animals
Chlorides
Coronary Circulation
Coronary Thrombosis
Disease Models, Animal
Female
Ferric Compounds
Hemodynamics
Male
Myocardial Infarction
Myocytes, Cardiac
Platelet Aggregation
Platelet Count
Sus scrofa
Troponin T

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10.1016/j.thromres.2005.02.006

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Dogné, J.-M., Rolin, S., Pétein, M., Tchana-Sato, V., Ghuysen, A., Lambermont, B., Hanson, J., Magis, D., Segers, P., Pirotte, B., Masereel, B., Drion, P., D'Orio, V., & Kolh, P. (2005). Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig. Thrombosis Research, 116(5), 431-42. https://doi.org/10.1016/j.thromres.2005.02.006

@article{73efc564bd464264b702f25d45664548,

title = "Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig",

abstract = "Great advances have been made in the prevention of thrombotic disorders by developments of new pharmacological and surgical treatments. Animal models of arterial thrombosis have largely contributed to the discovery and to the validation of original treatments. The purpose of the present work was to develop and validate an original model of acute myocardial infarction provoked in pig by thrombosis of the left anterior descending (LAD) coronary artery induced by topical application of ferric chloride solution.",

keywords = "Adenosine Triphosphate, Animals, Chlorides, Coronary Circulation, Coronary Thrombosis, Disease Models, Animal, Female, Ferric Compounds, Hemodynamics, Male, Myocardial Infarction, Myocytes, Cardiac, Platelet Aggregation, Platelet Count, Sus scrofa, Troponin T",

author = "Jean-Michel Dogn{\'e} and St{\'e}phanie Rolin and Michel P{\'e}tein and Vincent Tchana-Sato and Alexandre Ghuysen and Bernard Lambermont and Julien Hanson and David Magis and Patrick Segers and Bernard Pirotte and Bernard Masereel and Pierre Drion and Vincent D'Orio and Philippe Kolh",

year = "2005",

doi = "10.1016/j.thromres.2005.02.006",

language = "English",

volume = "116",

pages = "431--42",

journal = "Thrombosis Research",

issn = "0049-3848",

publisher = "Elsevier",

number = "5",

}

Dogné, J-M, Rolin, S, Pétein, M, Tchana-Sato, V, Ghuysen, A, Lambermont, B, Hanson, J, Magis, D, Segers, P, Pirotte, B, Masereel, B, Drion, P, D'Orio, V & Kolh, P 2005, 'Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig', Thrombosis Research, vol. 116, no. 5, pp. 431-42. https://doi.org/10.1016/j.thromres.2005.02.006

TY - JOUR

T1 - Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig

AU - Dogné, Jean-Michel

AU - Rolin, Stéphanie

AU - Pétein, Michel

AU - Tchana-Sato, Vincent

AU - Ghuysen, Alexandre

AU - Lambermont, Bernard

AU - Hanson, Julien

AU - Magis, David

AU - Segers, Patrick

AU - Pirotte, Bernard

AU - Masereel, Bernard

AU - Drion, Pierre

AU - D'Orio, Vincent

AU - Kolh, Philippe

PY - 2005

Y1 - 2005

N2 - Great advances have been made in the prevention of thrombotic disorders by developments of new pharmacological and surgical treatments. Animal models of arterial thrombosis have largely contributed to the discovery and to the validation of original treatments. The purpose of the present work was to develop and validate an original model of acute myocardial infarction provoked in pig by thrombosis of the left anterior descending (LAD) coronary artery induced by topical application of ferric chloride solution.

AB - Great advances have been made in the prevention of thrombotic disorders by developments of new pharmacological and surgical treatments. Animal models of arterial thrombosis have largely contributed to the discovery and to the validation of original treatments. The purpose of the present work was to develop and validate an original model of acute myocardial infarction provoked in pig by thrombosis of the left anterior descending (LAD) coronary artery induced by topical application of ferric chloride solution.

KW - Adenosine Triphosphate

KW - Animals

KW - Chlorides

KW - Coronary Circulation

KW - Coronary Thrombosis

KW - Disease Models, Animal

KW - Female

KW - Ferric Compounds

KW - Hemodynamics

KW - Male

KW - Myocardial Infarction

KW - Myocytes, Cardiac

KW - Platelet Aggregation

KW - Platelet Count

KW - Sus scrofa

KW - Troponin T

U2 - 10.1016/j.thromres.2005.02.006

DO - 10.1016/j.thromres.2005.02.006

M3 - Article

C2 - 16122556

SN - 0049-3848

VL - 116

SP - 431

EP - 442

JO - Thrombosis Research

JF - Thrombosis Research

IS - 5

ER -

Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig

Abstract

Keywords

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