Case report: Osteogenesis imperfecta, internal mammary artery graft & nitinol clips

Ludovic Melly, Anne Sophie Dincq, Claude Hanet, Benoît Rondelet

Research output: Contribution to journalArticlepeer-review


Background: Osteogenesis imperfecta is a genetic disorder of connective tissue causing mostly left-sided heart valves and aortic root pathologies, but a coronary artery involvement reflecting an increased sensitivity to cardiovascular risk factors is also suspected in this patient population. Case presentation: We report a 38-year-old patient with an osteogenesis imperfecta and a typical presentation of an acute myocardial infarction. The coronary angiogram showed a coronary 3-vessel disease. The patient underwent a bypass grafting surgery with the internal mammary artery. The sternum was closed using four nitinol clips and had totally stabilized at 4 months with excellent bone healing. Conclusions: With the successful clinical outcome in this patient severely affected by its osteogensis imperfecta, we underline the safe use of the LIMA, if precaution is taken towards the sternal bone, and its closure with nitinol clips.

Original languageEnglish
Article number117
Pages (from-to)117
JournalJournal of Cardiothoracic Surgery
Issue number1
Publication statusPublished - 1 Dec 2017
Externally publishedYes


  • Internal mammary artery
  • Nitinol clips
  • Osteogenesis imperfecta
  • ST Elevation Myocardial Infarction/complications
  • Humans
  • Alloys
  • Male
  • Surgical Instruments
  • Internal Mammary-Coronary Artery Anastomosis/instrumentation
  • Mammary Arteries/transplantation
  • Coronary Angiography
  • Coronary Vessels/surgery
  • Osteogenesis Imperfecta/complications
  • Adult
  • Stents


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