Abstract
A synthetic approach combining recent concepts for the preparation of multifunctional nanomolecules (click chemistry on multifunctional scaffolds) with supramolecular chemistry (self-assembly to prepare rotaxanes) gave easy access to a large variety of sophisticated [2]rotaxane heteroglycoclusters. Specifically, compounds combining galactose and fucose have been prepared to target the two bacterial lectins (LecA and LecB) from the opportunistic pathogen Pseudomonas aeruginosa.
Original language | English |
---|---|
Pages (from-to) | 88-92 |
Number of pages | 5 |
Journal | Chemistry: A European Journal |
Volume | 22 |
Issue number | 1 |
DOIs | |
Publication status | Published - 4 Jan 2016 |
Keywords
- click chemistry
- glycoclusters
- lectin
- pillar[5]arenes
- rotaxane
Fingerprint
Dive into the research topics of 'Biologically Active Heteroglycoclusters Constructed on a Pillar[5]arene-Containing [2]Rotaxane Scaffold'. Together they form a unique fingerprint.Equipment
-
Mass Spectrometry Service
Renard, P. (Manager)
Technological Platform Mass Spectrometry ServiceFacility/equipment: Technological Platform
-
Physical Chemistry and characterization(PC2)
Wouters, J. (Manager), Aprile, C. (Manager) & Fusaro, L. (Manager)
Technological Platform Physical Chemistry and characterizationFacility/equipment: Technological Platform