Antiviral activity of magnesium and magnesium/poly r(A-U) combinations against two RNA viruses

James M. Jamison; J. Gilloteaux; M. Reza Nassiri; C. C. Tsai; C. J. Summers

doi:10.1080/07328319908044668

Antiviral activity of magnesium and magnesium/poly r(A-U) combinations against two RNA viruses

James M. Jamison, J. Gilloteaux, M. Reza Nassiri, C. C. Tsai, C. J. Summers

Research output: Contribution to journal › Article › peer-review

Abstract

Magnesium (Mg²⁺) potentiated the anti-vesicular stomatitis virus (VSV) activity of poly r(A-U) or poly r(G-C) and the anti-HIV-1 activity of poly r(A-U). Mg did not affect the anti-VSV activity of poly (rI) · poly (rC), poly (dA-dT) · poly (dA-dT) or poly (dG-dC) · poly (dG-dC). Modulation of one or more nuclear (nucleolar) processes of the host cell may be responsible for the synergistic antiviral activity.

Original language	English
Pages (from-to)	1221-1222
Number of pages	2
Journal	Nucleosides and Nucleotides
Volume	18
Issue number	6-7
DOIs	https://doi.org/10.1080/07328319908044668
Publication status	Published - 1999
Externally published	Yes

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10.1080/07328319908044668

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abstract = "Magnesium (Mg2+) potentiated the anti-vesicular stomatitis virus (VSV) activity of poly r(A-U) or poly r(G-C) and the anti-HIV-1 activity of poly r(A-U). Mg did not affect the anti-VSV activity of poly (rI) · poly (rC), poly (dA-dT) · poly (dA-dT) or poly (dG-dC) · poly (dG-dC). Modulation of one or more nuclear (nucleolar) processes of the host cell may be responsible for the synergistic antiviral activity.",

author = "Jamison, {James M.} and J. Gilloteaux and Nassiri, {M. Reza} and Tsai, {C. C.} and Summers, {C. J.}",

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T1 - Antiviral activity of magnesium and magnesium/poly r(A-U) combinations against two RNA viruses

AU - Jamison, James M.

AU - Gilloteaux, J.

AU - Nassiri, M. Reza

AU - Tsai, C. C.

AU - Summers, C. J.

PY - 1999

Y1 - 1999

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AB - Magnesium (Mg2+) potentiated the anti-vesicular stomatitis virus (VSV) activity of poly r(A-U) or poly r(G-C) and the anti-HIV-1 activity of poly r(A-U). Mg did not affect the anti-VSV activity of poly (rI) · poly (rC), poly (dA-dT) · poly (dA-dT) or poly (dG-dC) · poly (dG-dC). Modulation of one or more nuclear (nucleolar) processes of the host cell may be responsible for the synergistic antiviral activity.

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SN - 0732-8311

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JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 6-7

ER -

Antiviral activity of magnesium and magnesium/poly r(A-U) combinations against two RNA viruses

Abstract

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