TY - JOUR
T1 - Analysis of the Genetic Diversity and Population Structure of Four Senegalese Sheep Breeds Using Medium-Density Single-Nucleotide Polymorphisms
AU - Missohou, Ayao
AU - Kaboré, Basse
AU - Flori, Laurence
AU - Ayssiwede, Simplice Bosco
AU - Hornick, Jean Luc
AU - Raes, Marianne
AU - Cabaraux, Jean François
N1 - Funding Information:
Acknowledgments: This study was supported by a grant from the Academy for Research and Higher Education (ARES), Belgium, to whom the authors are grateful. The authors also thank GIGA (University of Liège, Belgium) for providing logistic support for animal genotyping.
Funding Information:
Funding: This project received funding from the Academy for Research and Higher Education— Development Cooperation Committee (ARES-CCD), Brussels, Belgium.
Funding Information:
This project received funding from the Academy for Research and Higher Education— Development Cooperation Committee (ARES-CCD), Brussels, Belgium. This study was supported by a grant from the Academy for Research and Higher Education (ARES), Belgium, to whom the authors are grateful. The authors also thank GIGA (University of Liège, Belgium) for providing logistic support for animal genotyping.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/6/1
Y1 - 2022/6/1
N2 - In Senegal, sheep breeds have adapted to their environment and play a key socio-economic role. This study aimed to explore the genetic diversity and structure of four Senegalese sheep breeds (Peul-peul, Djallonke, Touabire, and Ladoum) and their relationships with global sheep breeds. To that end, forty-seven sheep were genotyped using the OvineSNP50 BeadChip, and these genotypic data were analysed with those of 73 sheep breeds representative of worldwide ovine diversity (2729 animals). The average observed heterozygosity (Ho) ranged from 0.293 in Djallonke sheep to 0.339 in Touabire sheep. The estimated Fis values were low, ranging from 0.019 for Ladoum to 0.034 for Peul-peul sheep. The estimated Fst values were low (0.003–0.044) among the trypanosusceptible breeds (Peul-peul, Touabire, and Ladoum) but high between the previous breeds and the trypanotolerant Djallonke breed (0.075–0.116), indicating better genetic conservation of the Djallonke sheep. A principal component analysis revealed clustering of the Senegalese sheep breeds according to their geographic distribution. However, owing to genetic improvement practices, the introgression of Touabire sheep blood seems to have reshaped the genetic landscape of the trypanosusceptible sheep breeds in Senegal. The Senegalese sheep breeds showed lower genetic diversity than their presumed ancestral sheep breeds of the Middle East. They also presented some relatedness with Caribbean sheep breeds, which reveals their contribution to the global genetic diversity and to the development of Caribbean sheep breeds.
AB - In Senegal, sheep breeds have adapted to their environment and play a key socio-economic role. This study aimed to explore the genetic diversity and structure of four Senegalese sheep breeds (Peul-peul, Djallonke, Touabire, and Ladoum) and their relationships with global sheep breeds. To that end, forty-seven sheep were genotyped using the OvineSNP50 BeadChip, and these genotypic data were analysed with those of 73 sheep breeds representative of worldwide ovine diversity (2729 animals). The average observed heterozygosity (Ho) ranged from 0.293 in Djallonke sheep to 0.339 in Touabire sheep. The estimated Fis values were low, ranging from 0.019 for Ladoum to 0.034 for Peul-peul sheep. The estimated Fst values were low (0.003–0.044) among the trypanosusceptible breeds (Peul-peul, Touabire, and Ladoum) but high between the previous breeds and the trypanotolerant Djallonke breed (0.075–0.116), indicating better genetic conservation of the Djallonke sheep. A principal component analysis revealed clustering of the Senegalese sheep breeds according to their geographic distribution. However, owing to genetic improvement practices, the introgression of Touabire sheep blood seems to have reshaped the genetic landscape of the trypanosusceptible sheep breeds in Senegal. The Senegalese sheep breeds showed lower genetic diversity than their presumed ancestral sheep breeds of the Middle East. They also presented some relatedness with Caribbean sheep breeds, which reveals their contribution to the global genetic diversity and to the development of Caribbean sheep breeds.
KW - Senegal
KW - sheep
KW - SNP
UR - http://www.scopus.com/inward/record.url?scp=85131687627&partnerID=8YFLogxK
U2 - 10.3390/ani12121512
DO - 10.3390/ani12121512
M3 - Article
AN - SCOPUS:85131687627
SN - 2076-2615
VL - 12
JO - Animals
JF - Animals
IS - 12
M1 - 1512
ER -