Absence of SARS-CoV-2 in the effluent of peritoneal dialysis patients

Alexandre Candellier, Anaïs Scohy, Nicolas Gillet, Benoit Muylkens, Johann Morelle, Leïla Belkhir, Damien Coupeau, Michel Jadoul, Éric Goffin

Research output: Contribution to journalArticlepeer-review

Abstract

The pandemic of respiratory disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is life-threatening in peritoneal dialysis (PD) patients. In PD patients with systemic viral infections, peritoneal effluent may be theoretically contaminated. We searched for the presence of SARS-CoV-2 genetic material by real-time reverse transcriptase–polymerase chain reaction assays in serial PD effluents of three PD infected patients. Nasopharyngeal swabs obtained at admission showed high viral load in all three patients, whereas none of the PD effluent specimen tested positive, even after dialysate concentration. Those results support at most a very low SARS-CoV-2 dissemination risk by the peritoneal effluent of PD patients. Imposing special disposal procedures, such as the instillation of hypochlorite in the drainage bags to prevent viral spread to health-care workers, are probably not required.

Original languageEnglish
Pages (from-to)499-503
Number of pages5
JournalPeritoneal Dialysis International
Volume40
Issue number5
DOIs
Publication statusPublished - 1 Sep 2020

Keywords

  • COVID-19
  • peritoneal dialysis
  • peritoneal effluent
  • SARS-CoV-2

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