Abstract
This study describes two novel synthetic procedures to prepare APM, a useful tool for the analysis and the purification of thiolated biomolecules. The methods developed are technically simple and robust and allowed the first full characterization of pure APM. Moreover, the efficacy of APM, as a biochemical tool, was demonstrated by analysis of tRNA thiolation by APM-PAGE.
Original language | English |
---|---|
Pages (from-to) | 7265-7 |
Number of pages | 3 |
Journal | Bioorganic & Medicinal Chemistry Letters |
Volume | 21 |
Issue number | 24 |
DOIs | |
Publication status | Published - 2011 |