A simple synthesis of APM ([p-(N-acrylamino)-phenyl]mercuric chloride), a useful tool for the analysis of thiolated biomolecules

V Lemau de Talancé, F Bauer, D Hermand, S P Vincent

    Research output: Contribution to journalArticlepeer-review

    Abstract

    This study describes two novel synthetic procedures to prepare APM, a useful tool for the analysis and the purification of thiolated biomolecules. The methods developed are technically simple and robust and allowed the first full characterization of pure APM. Moreover, the efficacy of APM, as a biochemical tool, was demonstrated by analysis of tRNA thiolation by APM-PAGE.
    Original languageEnglish
    Pages (from-to)7265-7
    Number of pages3
    JournalBioorganic & Medicinal Chemistry Letters
    Volume21
    Issue number24
    DOIs
    Publication statusPublished - 2011

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