Projects per year
The crystal structure of the title compound [systematic name: (2R)-3-(1H-indol-3-yl)-2-(4-nitro-1,3-dioxoisoindolin-2-yl)propanoic acid], C H N O , an analogue of epigenetic modulator RG108, is constrained by strong hydrogen bonds between the indole N - H group and a carbonyl O atom of the phthalimide ring of a symmetry-related molecule, and between the protonated O atom of the carboxyl group and a carbonyl O atom of the phthalimide ring. π-π stacking interactions with centroid-centroid distances of 3.638 (1) and 3.610 (1) Å are also observed between indole and phthalimide rings.
Etude physico-chimique et structurale du polymorphisme cristallin d'anticancéreux potentiels : la cocristallisation comme solution au problème de solubilité.
TILBORG, A. & WOUTERS, J.
1/10/09 → 30/09/13