4-Nitro-N-phthalyl-L-tryptophan

A. Tilborg, I. Boittiaux, B. Norberg, Didier Lambert, J. Wouters

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Abstract

The crystal structure of the title compound [systematic name: (2R)-3-(1H-indol-3-yl)-2-(4-nitro-1,3-dioxoisoindolin-2-yl)propanoic acid], C H N O , an analogue of epigenetic modulator RG108, is constrained by strong hydrogen bonds between the indole N - H group and a carbonyl O atom of the phthalimide ring of a symmetry-related molecule, and between the protonated O atom of the carboxyl group and a carbonyl O atom of the phthalimide ring. π-π stacking interactions with centroid-centroid distances of 3.638 (1) and 3.610 (1) Å are also observed between indole and phthalimide rings.
Original languageEnglish
Pages (from-to)o2116
JournalActa Crystallographica. Section E
Volume67
Issue number8
DOIs
Publication statusPublished - 2011

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