TY - JOUR
T1 - (2RS,5SR,6SR)-Methyl 4-{cis-2-[3-fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H- pyran-4-yl)phenoxymethyl]-6-hydroxy-3-phenylmorpholino}benzenesulfinate
AU - Charlier, Caroline
AU - Delayen, Aurelie
AU - Norberg, Bernadette
AU - Hénichart, Jean Pierre
AU - Wouters, Johan
PY - 2006/2/1
Y1 - 2006/2/1
N2 - The title compound, C
30H
34FNO
7S, is a key intermediate in the design of dual 5-LOX (5-lipoxygenase)/COX-2 (cyclooxygenase-2) inhibitors. The compound crystallizes as a racemate. Linear hydrogen-bonded chains are aligned along the [201] direction, and stacked π-π interactions and C - H⋯O contacts stabilize the crystal structure.
AB - The title compound, C
30H
34FNO
7S, is a key intermediate in the design of dual 5-LOX (5-lipoxygenase)/COX-2 (cyclooxygenase-2) inhibitors. The compound crystallizes as a racemate. Linear hydrogen-bonded chains are aligned along the [201] direction, and stacked π-π interactions and C - H⋯O contacts stabilize the crystal structure.
UR - http://www.scopus.com/inward/record.url?scp=33645028381&partnerID=8YFLogxK
U2 - 10.1107/S0108270106001065
DO - 10.1107/S0108270106001065
M3 - Article
C2 - 16456296
AN - SCOPUS:33645028381
SN - 0108-2701
VL - 62
JO - Acta crystallographica. Section C: Crystal structure communications
JF - Acta crystallographica. Section C: Crystal structure communications
IS - 2
ER -