Towards the design of innovating inhibitors for the first step of the kynurenine pathway

Mirgaux, Manon (PI)
Wouters, Johan (Supervisor)

Project: Research

Short title	Innovative hIDO1/hIDO2/hTDO inhibitors
Status	Finished
Effective start/end date	1/10/21 → 30/09/23

Attachment to an Research Institute in UNAMUR

NISM

1 Article

Structural study of bioisosteric derivatives of 5-(1 H-indol-3-yl)-benzotriazole and their ability to form chalcogen bonds
Mirgaux, M., Scaillet, T., Kozlova, A., Tumanov, N., Frédérick, R., Bodart, L. & Wouters, J., 1 Apr 2022, In: Acta Crystallographica. Section E: Crystallographic Communications. 78, 4, p. 418-424 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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26 Downloads (Pure)

6 Participation in conference

9th EFMC Young Medicinal Chemists' Symposium
MIRGAUX, M. (Contributor)
9 Sept 2022
Activity: Participating in or organising an event types › Participation in conference
33rd European Crystallography Meeting
MIRGAUX, M. (Poster)
23 Aug 2022 → 27 Aug 2022
Activity: Participating in or organising an event types › Participation in conference
3rd FNRS Med Chem Symposium
MIRGAUX, M. (Contributor)
19 May 2022
Activity: Participating in or organising an event types › Participation in conference

Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the open conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7P0N/pdb
Dataset
Crystal structure of L-Trp/Indoleamine 2,3-dioxygenase (hIDO1) complex with the JK-loop refined in the intermediate conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7P0R/pdb
Dataset
Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the closed conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7NGE/pdb
Dataset