Topological analyses of electron density maps are applied to the resolution of protein structures. Results are expressed in terms of critical point graphs. Logical relationships between the graph representations and the secondary structure of proteins are determined and used for the automated interpretation of X-ray diffraction data. Topological informations are also used to predict the slow dynamical motions of protein structures.
|Effective start/end date||30/09/91 → …|
- topological analysis
- graph theory
- electron density maps
- pattern recognition
Attachment to an Research Institute in UNAMUR