Tools from structural biology will be used to understand the structure-function relationships of two membrane enzymes, COX-2 and FAAH, involved in metabolism of neuromodulator fatty acid amides and esters

Project: Research

Project Details


The goal of the project is to study the structural properties and mechanisms of action (or inhibition) of FAAH and COX-2, and to compare them. This work will give some insights to design dual COX-2/FAAH inhibitors which is an original and interesting strategy in the therapeutic field.
Effective start/end date1/10/0530/09/09


  • biophysics
  • (membrane) proteins
  • drug design
  • molecular modelling
  • structural chemistry
  • crystallography


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