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2026
Evaluation of DOAC Dipstick Performance for Plasma Concentration Thresholds of 50, 70, and 100 ng/mL.
Harenberg, J. F., Merrelaar, A. E., Schwameis, M., Herkner, H., Hetjens, S., Weiss, C., Vassart, J., Douxfils, J., Tafur, A., Koscielny, J. & Langer, F., 19 Feb 2026, p. S27-S28.Research output: Contribution to conference › Poster
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2025
Corrigendum to ‘Impact of asundexian on a panel of coagulation assays’(Research and Practice in Thrombosis and Haemostasis (2025) 9(5), (S2475037925002742), (10.1016/j.rpth.2025.102950))
Vassart, J., Ndzatou, D. B., Didembourg, M., Morimont, L., Brisbois, C., Jamart, L., Demeure, F., Lebreton, A., Mullier, F., Favresse, J., Hardy, M., Dogné, J. M. & Douxfils, J., 2025, (Accepted/In press) In: Research and Practice in Thrombosis and Haemostasis. 103242.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Effect of heparins, direct oral anticoagulants, and factor XII/factor XI inhibitors on catheter-initiated thrombin generation in platelet-rich plasma: an in vitro study
Hardy, M., Thonon, H., Douxfils, J., Vassart, J., Gouin–Thibault, I., Lessire, S., Lecompte, T. & Mullier, F., Oct 2025, In: Journal of Thrombosis and Haemostasis. 23, 10, p. 3173-3184 12 p.Research output: Contribution to journal › Article › peer-review
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Impact of asundexian on a panel of coagulation assays
Vassart, J., Ndzatou, D. B., Didembourg, M., Morimont, L., Brisbois, C., Jamart, L., Demeure, F., Lebreton, A., Mullier, F., Favresse, J., Hardy, M., Dogné, J.-M. & Douxfils, J., Jul 2025, In: Research and Practice in Thrombosis and Haemostasis. 9, 5, p. 102950 102950.Research output: Contribution to journal › Article › peer-review
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2024
Accuracy of Direct Oral Anticoagulants (DOAC) Dipstick in patients treated preoperatively with DOAC
Vassart, J., Tafur, A., Boucher, A.-Y., Morimont, L., Walenga, J., Harenberg, J. F. & Douxfils, J., 30 May 2024.Research output: Contribution to conference › Poster › peer-review
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Accuracy of DOAC Dipstick urine test from patients treated peri-operatively with DOACs compared to UHPLC-MS/MS
Vassart, J., Boucher, A.-Y., Morimont, L., Tafur, A., Walenga, J., Harenberg, J. F. & Douxfils, J., 27 Feb 2024.Research output: Contribution to conference › Poster › peer-review
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A comparative in vitro study of the anticoagulant effect of branded versus generic rivaroxaban
Mangion, K., Vella, K., Gatt, A., Vella, A. M., Borg, M., Borg-Aquilina, D., Douxfils, J., Camilleri, L. & Riva, N., Mar 2024, In: Thrombosis Research. 235, p. 41-51 11 p.Research output: Contribution to journal › Article › peer-review
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Algorithm for Rapid Exclusion of Clinically Relevant Plasma Levels of Direct Oral Anticoagulants in Patients Using the DOAC Dipstick: An expert consensus paper
Harenberg, J., Gosselin, R. C., Cuker, A., Becattini, C., Pabinger, I., Poli, S., Weitz, J. I., Ageno, W., Bauersachs, R., Ćelap, I., Choi, P., Douketis, J., Douxfils, J., Elalamy, I., Fareed, J., Falanga, A., Favalor, E., Gerotziafas, G. T., Herkner, H. & Hetjens, S. & 17 others, , 5 Feb 2024, (E-pub ahead of print) In: Thrombosis and Haemostasis.Research output: Contribution to journal › Article › peer-review
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Asundexian and milvexian: what impact on the activity of the intrinsic pathway?
Vassart, J., Brisbois, C., Bangoup Ndzatou, D., Morimont, L. & Douxfils, J., 10 Oct 2024.Research output: Contribution to conference › Poster › peer-review
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Asundexian in atrial fibrillation: A predictable failure based on pharmacodynamic data?
Vassart, J., Didembourg, M., Morimont, L., Brisbois, C., Jamart, L., Lebreton, A., Mullier, F., Donis, N., Favresse, J., Dogné, J.-M. & Douxfils, J., 30 May 2024.Research output: Contribution to conference › Poster › peer-review
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Asundexian in atrial fibrillation: Can pharmacodynamic data explain the failure?
Vassart, J., Didembourg, M., Morimont, L., Brisbois, C., Jamart, L., Lebreton, A., Mullier, F., Donis, N., Favresse, J., Dogné, J.-M. & Douxfils, J., 7 Mar 2024, In: Thrombosis Research. 236, April 2024, p. 236-239 4 p.Research output: Contribution to journal › Article › peer-review
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Asundexian in atrial fibrillation: A predictable failure based on pharmacodynamic data?
Vassart, J., Didembourg, M., Morimont, L., Brisbois, C., Jamart, L., Lebreton, A., Mullier, F., Donis, N., Favresse, J., Dogné, J.-M. & Douxfils, J., 22 Jun 2024.Research output: Contribution to conference › Poster › peer-review
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Biological variation of thrombin generation on ST Genesia
van Dievoet, M. A., Morimont, L., Bouvy, C., Gruson, D., Stephenne, X. & Douxfils, J., Jun 2024, In: International Journal of Laboratory Hematology. 46, 3, p. 564-567 4 p., 10.111/ijlh.14232.Research output: Contribution to journal › Article › peer-review
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Corrigendum to "Asundexian in atrial fibrillation: Can pharmacodynamic data explain the failure?” [Thromb. Res. 236 (2024) 236–239 TR_8963, (S0049384824000732), (10.1016/j.thromres.2024.03.001)]
Vassart, J., Didembourg, M., Morimont, L., Brisbois, C., Jamart, L., Lebreton, A., Mullier, F., Donis, N., Favresse, J., Dogné, J.-M. & Douxfils, J., Aug 2024, In: Thrombosis Research. 240, p. 109066 109066.Research output: Contribution to journal › Comment/debate › peer-review
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The DOAC (direct oral anticoagulant) Dipstick reliably excludes residual FXa inhibitors levels in the preoperative setting
Vassart, J., Tafur, A., Durante, M., Boucher, A.-Y., Morimont, L., Walenga, J., Harenberg, J. F. & Douxfils, J., Jul 2024, In: Thrombosis Research. 239, July 2024, 109023.Research output: Contribution to journal › Article › peer-review
Open Access -
Thrombin generation to evaluate the complex hemostatic balance of hemophilia A plasma containing direct oral anticoagulant and supplemented by factor VIII
Lamoine, S., Jury, V., Fourneyron, V., Douxfils, J., Teissandier, D., Talon, L., Sinegre, T. & Lebreton, A., Oct 2024, In: Research and Practice in Thrombosis and Haemostasis. 8, 7, p. 102576 102576.Research output: Contribution to journal › Article › peer-review
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2023
D-dimer testing: A narrative review
Wauthier, L., Favresse, J., Hardy, M., Douxfils, J., Le Gal, G., Roy, P. M., van Es, N., Ay, C., Ten Cate, H., Lecompte, T., Lippi, G. & Mullier, F., Jan 2023, In: Advances in clinical chemistry. 114, p. 151-223 73 p.Research output: Contribution to journal › Review article › peer-review
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Editorial: Insights in thrombosis: 2022
Douxfils, J., Ten Cate, H. & Pola, R., 2023, In: Frontiers in cardiovascular medicine. 10, p. 1240626 1240626.Research output: Contribution to journal › Editorial › peer-review
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Reassessment of dextran sulfate in anti-Xa assay for unfractionated heparin laboratory monitoring
Hardy, M., Cabo, J., Deliège, A., Douxfils, J., Gouin-Thibault, I., Lecompte, T. & Mullier, F., Nov 2023, In: Research and Practice in Thrombosis and Haemostasis. 7, 8, p. 102257 102257.Research output: Contribution to journal › Article › peer-review
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Thrombin generation, bleeding and hemostasis in humans: Protocol for a scoping review of the literature
Shaw, J. R., James, T., Douxfils, J., Dargaud, Y., Levy, J. H., Brinkman, H. J. M., Shorr, R., Siegal, D., Castellucci, L. A., Gross, P., Khalife, R., Sperling, C., Page, D., Fergusson, D. & Carrier, M., 1 Nov 2023, In: PLoS ONE. 18, 11 NOVEMBER, e0293632.Research output: Contribution to journal › Article › peer-review
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Variability among commercial batches of normal pooled plasma in lupus anticoagulant testing
Cabo, J., Morimont, L., Baudar, J., Guldenpfennig, M., Jacqmin, H., Soleimani, R., Lecompte, T., Douxfils, J. & Mullier, F., Feb 2023, In: International Journal of Laboratory Hematology. 45, 1, p. 126-136 11 p.Research output: Contribution to journal › Article › peer-review
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2022
Performance of a Qualitative Point-of-Care Strip Test to Detect DOAC Exposure at the Emergency Department: A Cohort-Type Cross-Sectional Diagnostic Accuracy Study
Merrelaar, A. E., Bögl, M. S., Buchtele, N., Merrelaar, M., Herkner, H., Schoergenhofer, C., Harenberg, J., Douxfils, J., Siriez, R., Jilma, B., Spiel, A. O. & Schwameis, M., 1 Oct 2022, In: Thrombosis and Haemostasis. 122, 10, p. 1723-1731 9 p.Research output: Contribution to journal › Article › peer-review
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Study of in vitro thrombin generation after neutralization of heparin
Hardy, M., Douxfils, J., Morimont, L., Didembourg, M., Carlo, A., de Maistre, E., Lecompte, T. & Mullier, F., Feb 2022, In: International Journal of Laboratory Hematology. 44, 1, p. 168-176 9 p.Research output: Contribution to journal › Article › peer-review
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The edoxaban-M4 metabolite and measurement of edoxaban by chromogenic assays in human plasma
Siriez, R., Yildiz, H., Bouvy, C., Haguet, H., Maloteau, V., Hardy, M., Mullier, F., Dogné, J.-M., Hainaut, P. & Douxfils, J., Mar 2022, In: Research and Practice in Thrombosis and Haemostasis. 6, 3, p. e12680 e12680.Research output: Contribution to journal › Article › peer-review
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The Myths Behind DOAC Measurement: Analyses of Prescribing Information from Different Regulatory Bodies and a Call for Harmonization
Gosselin, R. C., Favaloro, E. J. & Douxfils, J., Nov 2022, In: Journal of Thrombosis and Haemostasis. 20, 11, p. 2494-2506 13 p.Research output: Contribution to journal › Article › peer-review
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Uninterrupted DOACs Approach for Catheter Ablation of Atrial Fibrillation: Do DOACs Levels Matter?
Hardy, M., Douxfils, J., Dincq, A.-S., Sennesael, A.-L., Xhaet, O., Mullier, F. & Lessire, S., 29 Mar 2022, In: Frontiers in cardiovascular medicine. 9, p. 864899 864899.Research output: Contribution to journal › Review article › peer-review
Open Access -
2021
2021 Update of the International Council for Standardization in Haematology Recommendations for Laboratory Measurement of Direct Oral Anticoagulants
Douxfils, J., Adcock, D., Bates, S. M., Favaloro, E. J., Gouin-Thibault, I., Guillermo, C., Kawai, Y., Lindhoff-Last, P. D. E., Kitchen, S. & Gosselin, R. C., 1 Aug 2021, In: Thrombosis and Haemostasis. 121, 8, p. 1008-1020 13 p.Research output: Contribution to journal › Article › peer-review
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Are the DOAC plasma level thresholds appropriate for clinical decision-making? A reappraisal using thrombin generation testing
Evrard, J., Hardy, M., Dogné, J.-M., LESSIRE, S., Maloteau, V., MULLIER, F. & Douxfils, J., Feb 2021, In: International Journal of Laboratory Hematology. 43, 1, p. e48-e51Research output: Contribution to journal › Letter › peer-review
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A Systematic Review and Meta-analysis of Performances of Prototype and Commercial DOAC Dipstick Tests for Detecting Direct Oral Anticoagulants in Patient Urine Samples – Increasing Confidence for Testing in Emergency Care (PB0367)
Martini, A., Bauersachs, R. M., Beyer-Westendorf, J., Crowther, M. A., Douxfils, J., Elalamy, I., Harenberg, J. F., Hetjens, S. & Weiss, C., 17 Jul 2021.Research output: Contribution to conference › Poster › peer-review
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Comparison is not reason: Pitfalls in reporting thrombin generation results in anticoagulated patients
Douxfils, J., Evrard, J., Hardy, M. & Mullier, F., May 2021, In: Research and Practice in Thrombosis and Haemostasis. 5, 4, p. e12523 e12523.Research output: Contribution to journal › Article › peer-review
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Comprehensive review of the impact of direct oral anticoagulants on thrombophilia diagnostic tests: Practical recommendations for the laboratory
SIRIEZ, R., Dogné, J.-M., Gosselin, R. C., Laloy, J., MULLIER, F. & Douxfils, J., Feb 2021, In: International Journal of Laboratory Hematology. 43, 1, p. 7-20 14 p.Research output: Contribution to journal › Article › peer-review
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Detection of Direct Oral Anticoagulants in Patient Urine Samples by Prototype and Commercial Test Strips for DOACs - A Systematic Review and Meta-analysis
Martini, A., Harenberg, J., Bauersachs, R., Beyer-Westendorf, J., Crowther, M., Douxfils, J., Elalamy, I., Weiss, C. & Hetjens, S., 24 Sept 2021, In: TH Open. 5, 3, p. e438-e448Research output: Contribution to journal › Article › peer-review
Open Access -
Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH
ISTH CDE Task Force, Jan 2021, In: Journal of Thrombosis and Haemostasis. 19, 1, p. 297-303 7 p.Research output: Contribution to journal › Article › peer-review
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Effect of Edoxaban on Laboratory Methods
von Horn, H., Bui, L., Rasmuson, A., Douxfils, J., Harenberg, J. F., Antovic, J. & Christensen, K., 17 Jul 2021.Research output: Contribution to conference › Poster › peer-review
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Impact of centrifugation on thrombin generation in healthy subjects and in patients treated with direct oral anticoagulants
Hardy, M., Dellanoce, C., Douxfils, J., Carlo, A., Lessire, S., Bouvy, C., Testa, S. & Mullier, F., Dec 2021, In: International Journal of Laboratory Hematology. 43, 6, p. 1585-1592 8 p.Research output: Contribution to journal › Article › peer-review
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The impact of strong inducers on direct oral anticoagulant levels
Sennesael, A.-L., Larock, A.-S., Hainaut, P., Lessire, S., Hardy, M., Douxfils, J., Spinewine, A. & Mullier, F., Oct 2021, In: The American journal of medicine. 134, 10, p. 1295-1299 5 p.Research output: Contribution to journal › Article › peer-review
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The Impact of Strong Inducers on Direct Oral Anticoagulant Plasma Levels: A Retrospective Study
Sennesael, A.-L., Larock, A.-S., Hainaut, P., Lessire, S., Hardy, M., Douxfils, J., Spinewine, A. & Mullier, F., 17 Jul 2021.Research output: Contribution to conference › Poster › peer-review
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2020
Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine-A Multicenter Trial
Harenberg, J., Beyer-Westendorf, J., Crowther, M., Douxfils, J., Elalamy, I., Verhamme, P., Bauersachs, R., Hetjens, S. & Weiss, C., 2020, In: Thrombosis and Haemostasis. 120, 1, p. 132-140 9 p.Research output: Contribution to journal › Article › peer-review
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An ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method for the quantification of edoxaban: The importance to measure active metabolite
Siriez, R., Evrard, J., Laloy, J., Dogné, J.-M. & Douxfils, J., 2020, BSTH Abstract Book 2019*: Program & Abstract. Belgian Society on Thrombosis and Haemostasis (BSTH), p. 24-25 P15Research output: Contribution in Book/Catalog/Report/Conference proceeding › Chapter
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Assessment of low plasma concentrations of apixaban in the periprocedural setting
Lessire, S., Dincq, A.-S., Siriez, R., Pochet, L., Sennesael, A.-L., Vornicu, O., Hardy, M., Deceuninck, O., Douxfils, J. & Mullier, F., 1 Aug 2020, In: International Journal of Laboratory Hematology. 42, 4, p. 394-402 9 p.Research output: Contribution to journal › Article › peer-review
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Importance of measuring pharmacologically active metabolites of edoxaban: development and validation of an ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method
Siriez, R., Alpan, L., Elasaad, K., Devel, P., Laloy, J., Dogné, J.-M. & Douxfils, J., 1 Apr 2020, In: Journal of Thrombosis and Thrombolysis. 49, 3, p. 395-403 9 p.Research output: Contribution to journal › Article › peer-review
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Potential Drug Interactions between Recombinant Interleukin-2 and Direct Oral Anticoagulants: Indirect Evidence from In Vivo Animal Studies
Mahmoudpour, S. H., Valerio, L., Douxfils, J., Mahan, C. E., Jankowski, M., Quitzau, K., Konstantinides, S. V. & Barco, S., 1 Dec 2020, In: Hämostaseologie. 40, 5, p. 679-686 8 p., 190032.Research output: Contribution to journal › Article › peer-review
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2019
Andexanet alfa for the reversal of factor Xa inhibitors
Favresse, J., Hardy, M., van Dievoet, M. A., Sennesael, A. L., Douxfils, J., Samama, C. M., Vornicu, O., Dincq, A. S., Lessire, S. & Mullier, F., 4 May 2019, In: Expert Opinion on Biological Therapy. 19, 5, p. 387-397 11 p.Research output: Contribution to journal › Article › peer-review
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An ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method for the quantification of edoxaban: The importance to measure active metabolite
Siriez, R., Evrard, J., Laloy, J., Dogné, J.-M. & Douxfils, J., 2019.Research output: Contribution to conference › Poster
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An update on laboratory assessment for direct oral anticoagulants (DOACs)
Gosselin, R. C., Adcock, D. M. & Douxfils, J., 1 May 2019, In: International Journal of Laboratory Hematology. 41, S1, p. 33-39 7 p.Research output: Contribution to journal › Review article › peer-review
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Assessment of the analytical performances and sample stability on ST Genesia system using the STG-DrugScreen application
Douxfils, J., Morimont, L., Bouvy, C., de Saint-Hubert, M., Devalet, B., Devroye, C., Dincq, A.-S., Dogné, J.-M., Guldenpfennig, M., Baudar, J., Larock, A.-S., Lessire, S. & Mullier, F., Aug 2019, In: Journal of Thrombosis and Haemostasis. 17, 8, p. 1273-1287 15 p.Research output: Contribution to journal › Article › peer-review
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Clotting test results correlate better with DOAC concentrations when expressed as a "Correction Ratio"; results before/after extraction with the DOAC Stop reagent
Exner, T., Favresse, J., Lessire, S., Douxfils, J. & Mullier, F., 1 Jul 2019, In: Thrombosis Research. 179, p. 69-72 4 p.Research output: Contribution to journal › Article › peer-review
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Comparison of the impact of DOACs on hemostasis diagnostic tests
Siriez, R., Evrard, J., Dogné, J.-M. (Supervisor), Mullier, F. & Douxfils, J., 2019, Comparison of the impact of DOACs on hemostasis diagnostic tests.Research output: Contribution in Book/Catalog/Report/Conference proceeding › Conference contribution
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Concomitant assessment of rivaroxaban concentration and its impact on thrombin generation
Bloemen, S., Zwaveling, S., Mullier, F. & Douxfils, J., Dec 2019, In: Thrombosis Research. 184, p. 8-15 8 p.Research output: Contribution to journal › Article › peer-review
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Determinants of the Quality of Warfarin Control after Venous Thromboembolism and Validation of the SAMe-TT2-R2 Score: An Analysis of Hokusai-VTE
Barco, S., Granziera, S., Coppens, M., Douxfils, J., Nijkeuter, M., Riva, N., Vanassche, T., Zhang, G., Lin, M., Kamphuisen, P. W., Cohen, A. T. & Beyer-Westendorf, J., 1 Jan 2019, In: Thrombosis and Haemostasis. 119, 4, p. 675-684 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Downloads (Pure)