Study of pharmacophore models of non-peptide AT1 angiotensin II receptor antagonists

Project: PHD

Project Details


Angiotensin II is an octapeptide which possesses potent vasoconstrictor properties. Non-peptide AT1-selective angiotensin II receptor antagonists have been developed to treat hypertension. A comparative analysis of their structural and electronic properties leads us to generate pharmacophore models.
Effective start/end date30/09/9431/12/00


  • angiotensin II
  • AT1 receptor
  • conformational analysis
  • structural analysis
  • XRD
  • antagonists


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.