Project Details
Description
Hypoxia-inducible factor-1 (HIF-1) is a heterodimeric transcription factor activated by hypoxia. When activated, HIF-1 mediates the differential expression of genes such as erythropoietin and Vascular Endothelial Growth Factor (VEGF).
| Status | Finished |
|---|---|
| Effective start/end date | 1/09/97 → 28/02/02 |
Keywords
- transcription factor
- 3D structure
- Hypoxia
- molecular modelling
- DNA
- X-ray diffraction
- HIF-
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