Project Details

Description

Hypoxia-inducible factor-1 (HIF-1) is a heterodimeric transcription factor activated by hypoxia. When activated, HIF-1 mediates the differential expression of genes such as erythropoietin and Vascular Endothelial Growth Factor (VEGF).
StatusFinished
Effective start/end date1/09/9728/02/02

Keywords

  • transcription factor
  • 3D structure
  • Hypoxia
  • molecular modelling
  • DNA
  • X-ray diffraction
  • HIF-