Hypoxia-inducible factor-1 (HIF-1) is a heterodimeric transcription factor activated by hypoxia. When activated, HIF-1 mediates the differential expression of genes such as erythropoietin and Vascular Endothelial Growth Factor (VEGF).
|Effective start/end date||1/09/97 → 28/02/02|
- transcription factor
- 3D structure
- molecular modelling
- X-ray diffraction
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