We investigate the effects of oxidized LDL (either by copper sulfate or in the presence of myeloperoxidase) on murine RAW264.7 macrophagic cells. We evaluate the effects on gene expression and on the activation of the transcription factor Nrf2 and on the UPR, trying to unravel the signalling mechanisms leading to either an adaptive response or to cell death.
|Effective start/end date||1/10/06 → 30/06/11|
- oxidized LDL
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.