PAI n°P7/28 - MICRODEV: Role of developmental processes in the virulence of human pathogens : from molecular mechanisms to novel therapeutic targets

Project: Research

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2017

CtrA Controls Cell Division and Outer Membrane Composition of the Pathogen Brucella abortus

Francis, N., Poncin, K., Fioravanti, A., Vassen, V., Willemart, K., Ong, T. A. P., Rappez, L., Letesson, J-J., Biondi, E. G. & De Bolle, X., Mar 2017, In : Molecular Microbiology. 103, 5, p. 780-797 18 p.

Research output: Contribution to journalArticle

2016
2015

Brucella abortus Cell Cycle and Infection Are Coordinated

De Bolle, X., Crosson, S., Matroule, J-Y. & Letesson, J-J., 2015, In : Trends in Microbiology.

Research output: Contribution to journalArticle

In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice

Hanot Mambres, D., Machelart, A., Vanderwinden, J-M., De Trez, C., Ryffel, B., Letesson, J-J. & Muraille, E., 2015, In : PLoS ONE. 10, 9, p. e0137835

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Open Access
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Mitochondria : A target for bacteria

Lobet, E., Letesson, J-J. & Arnould, T., 1 Apr 2015, In : Biochemical Pharmacology. 94, 3, p. 173-185 13 p.

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2014

Brucella, nitrogen and virulence

Ronneau, S., Moussa, S., Barbier, T., Conde-Álvarez, R., Zuniga-Ripa, A., Moriyon, I. & Letesson, J-J., 2014, In : Critical Reviews in Microbiology. p. 1-19 19 p.

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Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1,6-bisphosphatases for full virulence in laboratory models

Zúñiga-Ripa, A., Barbier, T., Conde-Álvarez, R., Martínez-Gómez, E., Palacios-Chaves, L., Gil-Ramírez, Y., Grilló, M. J., Letesson, J-J., Iriarte, M. & Moriyón, I., 2014, In : Journal of Bacteriology.

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Brucella melitensis invades murine erythrocytes during infection

Vitry, M-A., Hanot-Mambres, D., Deghelt, M., Hack, K., Machelart, A., Lhomme, F., Vanderwinden, J-M., Vermeersch, M., De Trez, C., Pérez-Morga, D., Letesson, J-J. & Muraille, E., 2014, In : Infection and Immunity. 82, 9, p. 3927-3938 12 p.

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Open Access
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Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella

Barbier, T., Collard, F., Zúñiga-Ripa, A., Moriyón, I., Godard, T., Becker, J., Wittmann, C., Van Schaftingen, E. & Letesson, J-J., 16 Dec 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 50, p. 17815-17820 6 p.

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G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus

Deghelt, M., Mullier, C., Sternon, J-F., Francis, N., Laloux, G., Dotreppe, D., Van der Henst, C., Jacobs-Wagner, C., Letesson, J-J. & De Bolle, X., 2014, In : Nature Communications. 5, p. 4366 11 p.

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Open Access
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On the link between cell cycle and infection of the Alphaproteobacterium Brucella abortus

Letesson, J-J., De Bolle, X. & Deghelt, M., 2014, In : microbial cell. 1, 10, p. 346-348

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Open Access
Open Access
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The quest for a true One Health perspective of brucellosis

Godfroid, J., De bolle, X., Roop, R. M., O'Callaghan, D., Tsolis, R. M., Baldwin, C., Santos, R. L., McGiven, J., Olsen, S., Nymo, I. H., Larsen, A., Al Dahouk, S. & Letesson, J. J., Aug 2014, In : OIE Revue Scientifique et Technique. 33, 2, p. 521-538 18 p.

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2013
Open Access
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The Brucella pathogens are polarized bacteria

Van der Henst, C., de Barsy, M., Zorreguieta, A., Letesson, J-J. & De Bolle, X., 1 Dec 2013, In : Microbes and infection : a journal on infectious agents and host defenses. 15, 14-15, p. 998-1004 7 p.

Research output: Contribution to journalArticle