New polycations and ADN vectorisation in vascular wall cells

  • Raes, Martine (PI)
  • Eliaers, Francois (Technician)
  • Ninane, Noelle (Technician)
  • VAN STEENBRUGGE, MARTINE (Technician)

Project: Research

Project Details

Description

MADAM and MADAM/MAPEO polymers synthetised at the UMH are evaluated at the URBC for their capacity to complex DNA (beta-gal reporter plasmid) and for their potential to transfect COS and endothelial cells in culture. Confocal microscopy is used as a tool to follow the intracellular traffic of the exogenous DNA labelled with a fluorescent probe.
AcronymPOLYPLEX
StatusFinished
Effective start/end date1/04/01 → 4/07/04
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Keywords

  • polycationic polymers
  • cell tranfection
  • polyplexes
  • confocal microscopy
  • endothelial cells