Project Details
Description
MADAM and MADAM/MAPEO polymers synthetised at the UMH are evaluated at the URBC for their capacity to complex DNA (beta-gal reporter plasmid) and for their potential to transfect COS and endothelial cells in culture. Confocal microscopy is used as a tool to follow the intracellular traffic of the exogenous DNA labelled with a fluorescent probe.
Acronym | POLYPLEX |
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Status | Finished |
Effective start/end date | 1/04/01 → 4/07/04 |
Keywords
- polycationic polymers
- cell tranfection
- polyplexes
- confocal microscopy
- endothelial cells