Molecular modelling and physico-chemical study of new chemical agents targeted on type 1 Human Immunodeficiency Virus (HIV-1) reverse transcriptase

Project: PHD

Project Details

Description

Our project seeks to design new and irreversible inhibitors of HIV-1 reverse transcriptase (RT) by studying RT / inhibitor complexes. These compounds will be able to form a covalent bond with one of the enzyme residues.
StatusFinished
Effective start/end date1/10/9930/04/04

Keywords

  • SIDA
  • HIV
  • modelisation moleculaire
  • modélisation moléculaire
  • inhibiteurs
  • transcriptase inverse