Identification of transcription factors and of their target genes involved in the modulation of etoposide-induced apoptosis under hypoxia

Project: PHD

Project Details

Description

Cells located in the center of tumors are often resistant to chemotherapies, aimed to kill them through apoptosis. Hypoxia is one of the factors responsible for this resistance. The aim of this project is to study the effect of hypoxia on etoposide-induced apoptosis using cancer cells in vitro, in order to identify the transcription factors responsible for this protection
StatusFinished
Effective start/end date1/09/051/09/09

Keywords

  • apoptosis
  • hypoxie
  • etoposide
  • transcription