Glycofullerenes as intra and extracellular enzymes inhibitors

Project: Research

Project Details


The inhibition of enzymes by multimeric species has very recently emerged
as a very appealing, yet exploratory, mode of enzyme inhibition. The
present project thus addresses the question of the biological relevance of
using glycofullerenes as multimeric enzyme inhibitors. Two main aspects
will be investigated: A) Can we target therapeutically relevant enzymes
thanks to this strategy ? B) Can these multimeric species enter into
eukaryotic and prokaryotic cells?
A direct application for the treatment of type 2 diabètes will be investigated.
Short titleGlycofullerenes
Effective start/end date1/10/1630/09/19

Attachment to an Research Institute in UNAMUR



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