Genetic and biochemical approach of the SpSkp1's function and its partners in the control of the transcription and the cell cycle in Schizosaccharomyces pombe

Project: PHD

Project Details

Description

In order to investigate the regulation's network of CAK complex in fission yeast, we identify a Skp1 homologue. The genetic analysis of the skp1-deleted cells and the skp1-3f mutant suuported that Skp1 and Pof6 play an essential role in cytokinesis in an non-SCF complex and that Skp1 is required prior the centrosome segregation in mitosis in a SCF dependent manner. The molecular mechanisms involved in these two proccess of the cell cycle are under investigation
AcronymSCF
StatusFinished
Effective start/end date1/10/9830/09/02

Keywords

  • Cell cycle
  • SCF complex
  • S. pombe
  • Skp1