The aim is to gain novel insight into molecular mechanisms of healthy ageing. Based on a proteomic analysis of ageing processes in a variety of ageing models including model organisms & model systems, we will address the question how changes in protein concentration and protein modification, protein-protein interactions and protein networks, signaling mediated by extracellular proteins, and protein turnover and degradation via the proteosomal system play a functionnal role in the ageing process.
|Effective start/end date||1/03/06 → 31/08/11|
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