Project Details
Description
Identification of proteins interacting with a regulatory DNA sequence depends on in silico analysis for putative transcription factors binding sites, a process generating a lot of false positive and false negative results. We develop a new method to isolate nuclear proteins that physically bind to a DNA sequence, synthesized by PCR, and to identify them by mass spectrometry
Status | Finished |
---|---|
Effective start/end date | 1/09/05 → 31/01/13 |
Keywords
- transcription factor purification
- DNA affinity
- transcription factor identification
- mass spectrometry
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.