Design, synthesis and study of enzyme modulators implicated in tryptophan metabolism and particularly in the kynurenin pathway

Project: Research

Project Details

Description

{description_courte}
StatusFinished
Effective start/end date1/10/0730/09/10

Research Output

3-ALKENYL INDOLES AS TRYPTOPHAN 2,3-DIOXYGENASE INHIBITORS FOR THE ENHANCEMENT OF CANCER IMMUNOTHERAPY

Dolušić, E., Pilotte, L., Moineaux, L., Larrieu, P., Stroobant, V., Colau, D., Pochet, L., De Plaen, E., Uyttenhove, C., Van den Eynde, B., Wouters, J., Masereel, B., Lanners, S. & Frédérick, R., 27 May 2013, p. Book of Abstracts, Heterocycles in Bio-organic Chemistry, Riga, Latvia, 27 - 30 May 2013, PO129. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
  • 97 Downloads (Pure)

    Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

    Pilotte, L., Larrieu, P., Stroobant, V., Colau, D., Dolušić, E., Frédérick, R., De Plaen, E., Uyttenhove, C., Wouters, J., Masereel, B. & Van Den Eynde, B. J., 14 Feb 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 7, p. 2497-2502 6 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 55 Downloads (Pure)

    Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

    Dolušić, E., Larrieu, P., Moineaux, L., Stroobant, V., Pilotte, L., Colaux, D., Van den Eynde, B., Masereel, B., Wouters, J. & Frédérick, R., 2012, In : ChemMedChem. p. 371 1 p.

    Research output: Contribution to journalLiterature review

    Activities

    • 6 Participation in conference

    Heterocycles in Bio-organic Chemistry

    Eduard Dolusic (Poster)

    27 May 2013

    Activity: Participating in or organising an event typesParticipation in conference

    BOSS XIII - 13th Belgian Organic Synthesis Symposium Louvain, 15 - 20 juillet 2012

    Eduard Dolusic (Poster)

    15 Jul 2012

    Activity: Participating in or organising an event typesParticipation in conference

    Annual One-Day Meeting on Medicinal Chemistry of SRC & KVCV (Medchem 2011)

    Eduard Dolusic (Poster)

    25 Nov 2011

    Activity: Participating in or organising an event typesParticipation in conference

    Press / Media

    Mladi Ogulinac u ekipi koja je na tragu lijeka protiv raka

    Eduard Dolusic

    24/02/12

    1 item of Media coverage

    Press/Media: Other

    USPJEH MLADOGA OGULINCA

    Eduard Dolusic

    24/02/12

    1 item of Media coverage

    Press/Media: Other

    Broadening TDO's base

    Eduard Dolusic, Raphaël Frederick, Bernard Masereel & Johan Wouters

    23/02/12

    1 item of Media coverage

    Press/Media: Expert Comment