Design of an original method to establish pharmacophores : application to thromboxane A2 receptor antagonists

Project: Research

Project Details


Development of an original method in order to compare 3D physico-chemical properties. Those are non-linearly projected on 2D maps, conserving the topolgy of the information, by using the maps Kohonen technique. A Monte Carlo algorithm is developed for the search of similarities between maps in order to propose corresponding structural features of thromboxane A2 receptor antagonists.
Effective start/end date1/02/0031/01/01


  • thromboxane A2 receptor antagonists
  • pharmacophore
  • Monte Carlo algorithm


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