Computer analysis of protein sequences and structures of endoxylanases from family

Project: Research

Project Details


The endoxylanases have been found to have several
different biotechnological applications, such as cellulose pulp
biobleaching, bread-making and saccharification of lignocellulosic biomass.
These applications require enzymes capable of operating under different
conditions (biobleaching, for instance requires thermostable and
alkali-stable enzymes). Therefore, for the design and protein engineering
of endoxylanases with different characteristics, it is of great importance
a good knowledge of their structure and sequence analysis.

For this purpose, a comparative analysis of the sequences of
several domains of family 11 glycanases is planned. The large number of
sequences available allows a fine analysis of sequence similarities, with
the purpose of establishing structural relationships, determine location of
conserved (and possibly essential) sequences and establish phylogenetic
Effective start/end date1/01/9830/12/99


  • endoxylanases phylogenetic sequence alignment


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