Project Details
Description
The endoxylanases have been found to have several
different biotechnological applications, such as cellulose pulp
biobleaching, bread-making and saccharification of lignocellulosic biomass.
These applications require enzymes capable of operating under different
conditions (biobleaching, for instance requires thermostable and
alkali-stable enzymes). Therefore, for the design and protein engineering
of endoxylanases with different characteristics, it is of great importance
a good knowledge of their structure and sequence analysis.
For this purpose, a comparative analysis of the sequences of
several domains of family 11 glycanases is planned. The large number of
sequences available allows a fine analysis of sequence similarities, with
the purpose of establishing structural relationships, determine location of
conserved (and possibly essential) sequences and establish phylogenetic
relationships.
different biotechnological applications, such as cellulose pulp
biobleaching, bread-making and saccharification of lignocellulosic biomass.
These applications require enzymes capable of operating under different
conditions (biobleaching, for instance requires thermostable and
alkali-stable enzymes). Therefore, for the design and protein engineering
of endoxylanases with different characteristics, it is of great importance
a good knowledge of their structure and sequence analysis.
For this purpose, a comparative analysis of the sequences of
several domains of family 11 glycanases is planned. The large number of
sequences available allows a fine analysis of sequence similarities, with
the purpose of establishing structural relationships, determine location of
conserved (and possibly essential) sequences and establish phylogenetic
relationships.
Status | Finished |
---|---|
Effective start/end date | 1/01/98 → 30/12/99 |
Keywords
- endoxylanases phylogenetic sequence alignment