Biochemical and genetic study of the Pch1 function, a new essentail cyclin of the fission yeast Schizosaccharomyces pombe

Project: PHD

Project Details

Description

In S. pombe Pch1 is an essential cyclin required for transcription. In order to investigate the regulation 's network of Pch1, we are currently performing a purification of the complex involved Pch1, based on the TAP ('tandem Affinity Purification') system and constructing mutants of Pch1 and ist partners Cdk9
StatusFinished
Effective start/end date1/10/021/01/07

Keywords

  • transcription
  • CTD kinase
  • essential
  • C-cyclin
  • S. pombe