• 3742 Citations
  • 35 h-Index
1993 …2020

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2006

NnrA is required for full virulence and regulates several Brucella melitensis denitrification genes

Haine, V., Dozot, M., Dornand, J., Letesson, J-J. & De Bolle, X., 2006, In : J Bacteriol. 188, 4, p. 1615-1619 5 p.

Research output: Contribution to journalArticle

The stringent response mediator Rsh is required for Brucella melitensis and Brucella suis virulence, and for expression of the type IV secretion system virB

Dozot, M., Boigegrain, R-A., Delrue, R-M., Hallez, R., Ouahrani-Bettache, S., Danese, I., Letesson, J-J., De Bolle, X. & Köhler, S., 2006, In : Cellular microbiology. 8, 11, p. 1791-802 12 p.

Research output: Contribution to journalArticle

2005

A quorum-sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis.

Delrue, R-M., Deschamps, C., Leonard, S., Nijskens, C., Danese, I., Schauss, J-M., Bonnot, S., Ferooz, J., Tibor, A., De Bolle, X. & Letesson, J-J., 2005, In : Cellular microbiology. 7, 8, p. 1151-1161 11 p.

Research output: Contribution to journalArticle

Systematic targeted mutagenesis of Brucella melitensis 16M reveals a major role for GntR regulators in the control of virulence

Haine, V., Sinon, A., Van Steen, F., Rousseau, S., Dozot, M., Lestrate, P., Lambert, C., Letesson, J. J. & De Bolle, X., 1 Sep 2005, In : Infection and Immunity. 73, 9, p. 5578-5586 9 p.

Research output: Contribution to journalArticle

The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection

Fretin, D., Fauconnier, A., Kôhler, S., Halling, S., Leonard, S., Nijskens, C., Ferooz, J., Lestrate, P., Delrue, R-M., Danese, I., Vandenhaute, J., Tibor, A., De Bolle, X. & Letesson, J-J., 2005, In : Cellular microbiology. 7, 5, p. 687-698 12 p.

Research output: Contribution to journalArticle

2004

Antigen genes for molecular epidemiology of leishmaniasis: polymorphism of cysteine proteinase B and surface metalloprotease glycoprotein 63 in the Leishmania donovani complex

Quispe Tintaya, K. W., Ying, X., Dedet, J-P., Rijal, S., De Bolle, X. & Dujardin, J-C., 2004, In : Journal of infectious diseases. 189, p. 1035-1043 9 p.

Research output: Contribution to journalArticle

Brucella pathogenesis, genes identified from random large-scale screens

Delrue, R-M., Lestrate, P., Tibor, A., Letesson, J-J. & De Bolle, X., 2004, In : FEMS microbiology letters. 231, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Functional, molecular and structural characterisation of five anti-Brucella LPS mAb

Laurent, T., Mertens, P., Dierick, J-F., Letesson, J-J., Lambert, C. & De Bolle, X., 2004, In : Molecular immunology. 40, p. 1237-1247 11 p.

Research output: Contribution to journalArticle

Generation of the Brucella melitensis ORFeome version 1.1

Dricot, A., Rual, J-F., Lamesch, P., Bertin, N., Dupuy, D., Hao, T., Lambert, C., Hallez, R., Delroisse, J-M., Vandenhaute, J., Lopez-Goñi, I., Moriyon, I., Garcia-Lobo, J. M., Sangari, F. J., Macmillan, A. P., Cutler, S. J., Whatmore, A. M., Bozak, S., Sequerra, R., Doucette-Stamm, L. & 4 others, Vidal, M., Hill, D. E., Letesson, J-J. & De Bolle, X., 2004, In : Genome Research. 14, p. 2201-6 6 p.

Research output: Contribution to journalArticle

Morphological and functional asymmetry in alpha-proteobacteria

Hallez, R., Bellefontaine, A-F., Letesson, J-J. & De Bolle, X., 2004, In : Trends in Microbiology. 12, 8, p. 361-5 5 p.

Research output: Contribution to journalArticle

The Ton system, an ABC transporter and an universally conserved GTPase are involved in iron utilization by Brucella melitensis 16M

Danese, I., Haine, V., Delrue, R-M., Tibor, A., Lestrate, P., Stevaux, O., Mertens, P., Paquet, J-Y., Godfroid, J., De Bolle, X. & Letesson, J-J., 2004, In : Infect Immun. 72, p. 5783-5790 8 p.

Research output: Contribution to journalArticle

2003

Attenuated signature-tagged mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice

Lestrate, P., Dricot, A., Lambert, C., Martinelli, V., De Bolle, X., Letesson, J-J. & Tibor, A., 2003, In : Infection and Immunity. 71, 12, p. 7053-7060 8 p.

Research output: Contribution to journalArticle

Biologie in silico: point de vue de bioinformaticiens

Lambert, C., Wouters, J., De Bolle, X. & Depiereux, E., 2003, In : Chimie nouvelle. 83, p. 106-111 6 p.

Research output: Contribution to journalArticle

Construction of a set of Saccharomyces cerevisiae vectors designed for recombinational cloning

Vanmullem, V., Wéry, M., De Bolle, X. & Vandenhaute, J., 2003, In : Yeast. 20, p. 739-746 8 p.

Research output: Contribution to journalArticle

Review of common sequence alignment methods: clues to enhance reliability

Lambert, C., Van Campenhout, J-M., De Bolle, X. & Depiereux, E., 2003, In : Current genomics. 4, 2, p. 131-146 16 p.

Research output: Contribution to journalArticle

2002

ESyPred3D: prediction of proteins 3D structures

Lambert, C., Leonard, N., De Bolle, X. & Depiereux, E., 2002, In : Bioinformatics. 18, 9, p. 1250-1256 7 p.

Research output: Contribution to journalArticle

Fun stories about Brucella: the furtive nasty bug

Letesson, J-J., Lestrate, P., Delrue, R-M., Danese, I., Bellefontaine, F., Fretin, D., Taminiau, B., Tibor, A., Dricot, A., Deschamps, C., Haine, V., Léonard, S., Laurent, T., Mertens, P., Vandenhaute, J. & De Bolle, X., 2002, In : Veterinary microbiology. 90, p. 317-328 12 p.

Research output: Contribution to journalArticle

Identification of a quorum-sensing signal molecule in the facultative intracellular pathogen Brucella melitensis.

Taminiau, B., Tibor, A., Lestrate, P., De Bolle, X. & Letesson, J-J., 2002, In : Infect Immun. 70, p. 3004-3011 8 p.

Research output: Contribution to journalArticle

Yersinia enterocolitica as a vehicle for a naked DNA vaccine encoding Brucella abortus bacterioferritin or P39 antigen.

Al-Mariri, A., Tibor, A., Lestrate, P., Mertens, P., De Bolle, X. & Letesson, J-J., 2002, In : Infect Immun. 70, p. 1915-1923 9 p.

Research output: Contribution to journalArticle

2001

Identification of Brucella spp. genes involved in intracellular trafficking

Delrue, R-M., Martinez-Lorenzo, M., Lestrate, P., Danese, I., Bielarz, V., Mertens, P., De Bolle, X., Tibor, A., Gorvel, J-P. & Letesson, J-J., 2001, In : Cellular microbiology. 3, 7, p. 487-497 11 p.

Research output: Contribution to journalArticle

Induction of immune response in BALB/c mice with a DNA vaccine encoding bacterioferritin or P39 of Brucella spp.

Al-Mariri, A., Tibor, A., Mertens, P., De Bolle, X., Michel, P., Godfroid, J., Walravens, K. & Letesson, J. J., 2 Oct 2001, In : Infection and Immunity. 69, 10, p. 6264-6270 7 p.

Research output: Contribution to journalArticle

Molecular, antigenic, and functional analyses of Omp2b porin size variants of Brucella spp.

Paquet, J-Y., Diaz, M., Genevrois, S., Grayon, M., Verger, J-M., De Bolle, X., Lakey, J., Letesson, J-J. & Cloeckaert, A., 2001, In : Journal of Bacteriology. 183, 16, p. 4839-4847 9 p.

Research output: Contribution to journalArticle

Protection of BALB/c mice against Brucella abortus 544 challenge by vaccination with bacterioferritin or P39 recombinant proteins with CpG oligodeoxynucleotides as adjuvant

Al Mariri, A. B., Tibor, A., Mertens, P., De Bolle, X., Michel, P., Godfroid, J., Walravens, K. & Letesson, J-J., 2001, In : Infection and Immunity. 69, 8, p. 4816-4822 7 p.

Research output: Contribution to journalArticle

Selection of phage-displayed peptides recognised by monoclonal antibodies directed against the lipopolysaccharide of Brucella

Mertens, P., Walgraffe, D., Laurent, T., De Schrevel, N., Letesson, J-J. & De Bolle, X., 2001, In : International review of immunology. 20, p. 181-199 19 p.

Research output: Contribution to journalArticle

2000

Genetic organisation of the lipopolysaccharide O-antigen biosynthesis region of Brucella melitensis 16M (wbk)

Godfroid, F., Cloeckaert, A., Taminiau, B., Danese, I., Tibor, A., De Bolle, X., Mertens, P. & Letesson, J-J., 2000, In : Research in microbiology. 151, p. 655-668 14 p.

Research output: Contribution to journalArticle

Identification and characterization of in vivo attenuated mutants of Brucella melitensis

Lestrate, P., Delrue, R-M., Danese, I., Didembourg, C., Taminiau, B., Mertens, P., De Bolle, X., Tibor, A., Tang, C. & Letesson, J-J., 2000, In : Molecular Microbiology. 38, 3, p. 543-551 9 p.

Research output: Contribution to journalArticle

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases

De Bolle, X., Bayliss, C. D., Field, D., Van De Ven, T., Saunders, N. J., Hood, D. W. & Moxon, E. R., 18 Jan 2000, In : Molecular Microbiology. 35, 1, p. 211-222 12 p.

Research output: Contribution to journalArticle

1999

Antigenic properties of peptidic mimics for epitopes of the lipopolysaccharide from Brucella

De Bolle, X., Laurent, T., Tibor, A., Godfroid, F., Weynants, V., Letesson, J-J. & Mertens, P., 1999, In : Journal of molecular biology. 294, p. 181-191 11 p.

Research output: Contribution to journalArticle

Structure and function prediction of the Brucella abortus P39 protein by comparative modeling with marginal sequence similarities

De Fays, K., Tibor, A., Lambert, C., Vinals, C., Denoël, P., De Bolle, X., Wouters, J., Letesson, J. J. & Depiereux, E., 15 Apr 1999, In : Protein Engineering. 12, 3, p. 217-223 7 p.

Research output: Contribution to journalArticle

1998

Comparative analysis of seven multiple protein sequence alignment servers: clues to enhance reliability of predictions

Briffeuil, P., Baudoux, G., Lambert, C., De Bolle, X., Vinals Bassols, C., Feytmans, E. & Depiereux, E., 1998, In : Bioinformatics. 14, 4, p. 357-366 10 p.

Research output: Contribution to journalArticle

Production and characterisation of monoclonal antibodies specific for bovine interleukin-4

Weynants, V., Gilson, D., Furger, A., Collins, R., Mertens, P., De Bolle, X., Heussler, V., Roditi, I., Howard, C., Dobbelaere, A. & Letesson, J-J., 1998, In : Veterinary immunology and immunopathology. 66, p. 99-112 14 p.

Research output: Contribution to journalArticle

1997

Bivalent cations stabilize yeast alcohol dehydrogenase I

De Bolle, X., Vinals, C., Fastrez, J. & Feytmans, E., 1997, In : Biochem. J.. 323, -2, p. 409-413 5 p.

Research output: Contribution to journalArticle

Match-Box_server: a multiple sequence alignment tool placing emphasis on reliability.

Depiereux, E., Baudoux, G., Briffeuil, P., Reginster, I., De Bolle, X., Vinals Bassols, C. & Feytmans, E., 1997, In : Computer Application Bioscience. 13, p. 249-256 8 p.

Research output: Contribution to journalArticle

1995

Identification of residues potentially involved in the interactions between subunits in yeast alcohol dehydrogenases

De Bolle, X., Vinals Bassols, C., Prozzi, D., Paquet, J-Y., Depiereux, E., Vandenhaute, J., Feytmans, E. & Leplae, R., 1995, In : European Journal of Biochemistry . 231, p. 214-219 6 p.

Research output: Contribution to journalArticle

Knowledge-based modeling of the D-lactate dehydrogenase three-dimensional structure

Vinals Bassols, C., De Bolle, X., Depiereux, E. & Feytmans, E., 1995, In : Protein Structure Function and Genetic. 21, p. 307-318 12 p.

Research output: Contribution to journalArticle

1994

Molecular cloning, nucleotide sequence, and occurrence of a 16.5- kilodalton outer membrane protein of Brucella abortus with similarity to PAL lipoproteins

Tibor, A., Weynants, V., Denoel, P., Lichtfouse, B., De Bolle, X., Saman, E., Limet, J. N. & Letesson, J. J., 1 Jan 1994, In : Infection and Immunity. 62, 9, p. 3633-3639 7 p.

Research output: Contribution to journalArticle

1993