Riccardo Marega

  • 1111 Citations
  • 16 h-Index
20062019
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Personal profile

Introduction

Riccardo Marega obtained his master degree in medicinal chemistry and pharmaceutical technologies in the University of Trieste (Italy) in 2005, by working in the implementation of functional carbon nanotube derivatives for biomedical applications under the supervision of Prof. Maurizio Prato. He then moved to a pharmaceutical company (Eurand, now Aptalis) in the Research Area of Trieste, doing a PhD in Molecular Sciences under the supervision of Prof. Maurizio Prato and Dr. Erminio Murano, where he was involved in the synthesis of carbohydrate-drug-CNTs nanohybrids as anticancer platforms, along with the development of diffusion-based NMR spectroscopy for the study of functionalized CNT derivatives. In 2010 he joined Prof. Bonifazi’s group in the COMS unit here at the department of Chemistry as a post-doctoral fellow, being mainly involved in the synthesis, characterization and biological evaluation of magnetic CNT derivatives as multifunctional anticancer nanomaterials, and in the surface derivatization of biocompatible substrates promoting directed cellular migration. His current and forthcoming studies are at the interface between materials science and biology, to investigate how multifunctional nanomaterials can be applied for cancer therapeutics and diagnosis (theranosis). His recent results obtained at the COMS unit have been presented in two internationally-relevant scientific congress, namely Chemontubes (Archacon, France) and NT12 (Brisbane, Australia). He is excited by this new position at the University of Namur, since it is a great opportunity to continue the exploration of the aforementioned fields, along with other new activities related to the study and developement of biomaterials.   

Areas of expertise

Material chemistry - Nanotechnology - Chemical Biology - Carbon Nanotubes Chemistry - Bioconjugation. Biological Evaluations

Diplomas

Diploma Thesis: "Functionalization and structural characterization of carbon nanotubes derivatives for biological applications" under the supervision of Prof. Maurizio Prato and Dr. Davide Bonifazi. Assessment: 110/110 cum laude.
Doctoral Thesis: "Structural characterization of new carbon nanotubes derivatives through NMR spectroscopy".

Introduction

2012-present: FRS-FNRS Post-doctoral fellow at the Department of Chemistry and Namur Advanced Research College, University of Namur (Belgium)

2010-2012: Post-doctoral fellow at Department of Chemistry, University of Namur (Belgium)

 My inspiration for science relies on the surprises that experimental research offers to the motivated scientist. Indeed, the experimental validation of what we foresee by material design and preparation give me a great satisfaction, on one hand. However, like a charming beautiful woman, science not always gives us the answers that we foresee after our efforts, often providing us unpredictable outcomes. My greatest satisfaction is to use the most advanced research tools to explore and deciper the scientific phenomena connected with the interactions between nanosized materials and living things, and then to report them to the scientific community. 

 I’m currently developing hybrid metal-carbon nanostructures with targeting properties for biomedical responses such as magnetically-driven drug delivery and hyperthermia, in both in-vitro and in-vivo models. On another avenue, I’m also evaluating the biochemical responses of cells to motogenic peptides found in animals extracellular matrix.   

Areas of expertise

Materials Chemistry, Biochemistry, Nantechnology

Awards

Selected partecipant of the 63rd Lindau Nobel Laureate Meeting

Diplomas

2006-2009: PhD student in Molecular Sciences under the supervision of Prof. Maurizio Prato (Department of Pharmacy, University of Trieste, Italy) and Dr. Erminio Murano (Polymer Conjugation Division, Eurand, Research Area of Trieste, Italy)

1999-2005Laurea in medicinal chemistry and pharmaceutical technology (summa cum laude), with a Diploma thesis in Organic Chemistry under the supervision of Prof. Maurizio Prato (Department of Pharmacy, University of Trieste).

External responsibilities

TP master 1 de chimie instrumentale et de caractérisation

Education/Academic qualification

Master of Pharmacy, University of Trieste

Doctor of Philosophy, University of Trieste

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Research Output 2006 2019

  • 1111 Citations
  • 16 h-Index
  • 26 Article
  • 2 Chapter (peer-reviewed)
  • 2 Patent
  • 1 Literature review
Proton Therapy
Antibodies
Gold
Nanoparticles
Protons

METHOD FOR FUNCTIONALISING NANOPARTICLES

Bonifazi, D., Corvaglia, V., Marega, R. & Lucas, S., 27 Jun 2018, IPC No. B82Y 5/ 00 A N, Patent No. EP3338806, Priority date 21 Dec 2016, Priority No. EP20160205708

Research output: Patent

Patents and inventions
Nanoparticles
Molecules
Antibodies
Proteins

METHOD FOR FUNCTIONALIZING NANOPARTICLES

Bonifazi, D., Corvaglia, V., Marega, R. & Lucas, S., 28 Jun 2018, IPC No. B82Y 5/ 00 A N, Patent No. WO2018114447, Priority date 21 Dec 2016, Priority No. EP20160205708

Research output: Patent

Patents and inventions
Nanoparticles
Molecules
Antibodies
Proteins

Unfolding IGDQ Peptides for Engineering Motogenic Interfaces

De Leo, F., Marega, R., Corvaglia, V., Tondo, R., Lo Cicero, M., Silvestrini, S. & Bonifazi, D., 1 Aug 2017, In : Langmuir. 33, 30, p. 7512-7528 17 p.

Research output: Contribution to journalArticle

Peptides
peptides
engineering
fillers
Fillers

Fast Targeting and Cancer Cell Uptake of Luminescent Antibody-Nanozeolite Bioconjugates

Marega, R., Prasetyanto, E. A., Michiels, C., De Cola, L. & Bonifazi, D., 2016, In : Small. p. 5431-5441 11 p.

Research output: Contribution to journalArticle

Antibodies
Nanoparticles
Nanocrystals
Zeolites
Nanostructures

Activities 2006 2015

  • 8 Participation in conference
  • 4 Participation in workshop, seminar, course
  • 2 Participation to a Symposium, a study Day

Hybrid Materials 2015: Fourth International Conference on Multifunctional, Hybrid and Nanomaterials

Riccardo Marega (Speaker)
9 Mar 201513 Mar 2015

Activity: Participating in or organising an event typesParticipation in conference

Nanomedicine Viterbo 2014

Riccardo Marega (Speaker)
17 Sep 2014

Activity: Participating in or organising an event typesParticipation in conference

Theraplus project Kick-off Meeting

Riccardo Marega (Member of Scientific Committee)
15 May 2014

Activity: Participating in or organising an event typesParticipation to a Symposium, a study Day

Molecular and Supramolecular routes toward Structural Complexity

Riccardo Marega (Speaker)
26 Sep 2013

Activity: Participating in or organising an event typesParticipation to a Symposium, a study Day

63rd Lindau Nobel Laureate Meeting

Riccardo Marega (Participant)
30 Jun 20135 Jul 2013

Activity: Participating in or organising an event typesParticipation in conference