Raphael FREDERICK

  • 1411 Citations
  • 21 h-Index
20002019

Research output per year

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Research Output

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Poster
2015

Design of new small molecular weight inhibitors of FXIIa

Bouckaert, C., Serra, S., Dogne, J-M., Frederick, R. & Pochet, L., 4 Jun 2015.

Research output: Contribution to conferencePoster

2013

3-ALKENYL INDOLES AS TRYPTOPHAN 2,3-DIOXYGENASE INHIBITORS FOR THE ENHANCEMENT OF CANCER IMMUNOTHERAPY

Dolušić, E., Pilotte, L., Moineaux, L., Larrieu, P., Stroobant, V., Colau, D., Pochet, L., De Plaen, E., Uyttenhove, C., Van den Eynde, B., Wouters, J., Masereel, B., Lanners, S. & Frédérick, R., 27 May 2013, p. Book of Abstracts, Heterocycles in Bio-organic Chemistry, Riga, Latvia, 27 - 30 May 2013, PO129. 1 p.

Research output: Contribution to conferencePoster

Open Access
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95 Downloads (Pure)
Open Access
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24 Downloads (Pure)
2012

Convenient one-pot formation of highly functionalized 5-halothiazoles

Dolusic, E., Modaffari, S., Pochet, L., Wouters, J., Masereel, B. & Frédérick, R., 1 Jul 2012, p. Book of Abstracts, Balticum Organicum Syntheticum, July 1-4 2012, Tallinn, Estonia, PO27, p. 74. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
59 Downloads (Pure)

STUDY OF COUMARINS WITH IMPROVED SOLUBILITY TO INHIBIT FXIIa, AN EMERGING TARGET IN THROMBOSIS RESEARCH

Bouckaert, C., Vancraeynest, C., Dolušić, E., Frédérick, R. & Pochet, L., 30 Nov 2012, p. Book of Abstracts, MedChem 2012, Château de Colonster, Liège - November 30, 2012, P01. 1 p.

Research output: Contribution to conferencePoster

File
16 Downloads (Pure)

Tryptophan 2,3-Dioxygenase (TDO) Inhibitors as Anticancer Immunomodulators

Dolusic, E., Larrieu, P., Moineaux, L., Strobant, V., Pilotte, L., Colau, D., Pochet, L., De Plaen, E., Uyttenhove, C., Van den Eynde, B., Wouters, J., Masereel, B. & Frédérick, R., 15 Jul 2012, p. Programme & Book of Abstracts, BOSS XIII, KU Leuven, Belgium, 15 - 20 July 2012, P292, p. 339. 1 p.

Research output: Contribution to conferencePoster

File
233 Downloads (Pure)
2011

A CONVENIENT FORMATION OF HIGHLY FUNCTIONALIZED 5-BROMO-1,3-THIAZOLES.

Dolusic, E., Modaffari, S., Wouters, J., Masereel, B. & Frédérick, R., 2011, p. Book of Abstracts, 15th Sigma-Aldrich Organic Synthesis Meeting, Spa, Belgium, 1-2 December 2011, p. 25. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
69 Downloads (Pure)

Aromatic Thiosemicarazones are inhibitors of tryptophan 2,3-Dioxygenase (TDO), an emerging target for cancer treatment

Dolusic, E., Modaffari, S., Larrieu, P., Vancraeynest, C., Pilotte, L., Colau, D., Stroobant, V., Wouters, J., Masereel, B., Van den Eynde, B. & Frédérick, R., 2011, (Unpublished) p. Book of Abstracts, ASMC 11, St. Petersburg, Russia, August 21-25, 2011, P157. 1 p.

Research output: Contribution to conferencePoster

File
82 Downloads (Pure)

Indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2,3 dioxygenase (IDO), a promising target for anti-cancer immunotherapy

Dolusic, E., Larrieu, P., Blanc, S., Moineaux, L., Sapunaric, F., Pouyez, J., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colau, D., Frère, J-M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2011, p. Book of Abstracts, 47èmes RICT, 6-8 juillet 2011, Lyon, France, IS08, p. 136. 1 p.

Research output: Contribution to conferencePoster

File
48 Downloads (Pure)

Indole-pyridinyl-ethanones as novel inhibitors of indoleamine-2,3-dioxygenase (IDO), a promising target for anti-cancer immunotherapy

Dolusic, E., Larrieu, P., Blanc, S., Moineaux, L., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colaux, D., Wouters, J., Masereel, B., Van den Eynde, B. & Frédérick, R., 2011, p. Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, P37, p. 62. 1 p.

Research output: Contribution to conferencePoster

Novel Inhibitors of Indoleamine 2,3-Dioxygenase (IDO), a Target for Anti-Cancer Immunotherapy

Dolusic, E., Blanc, S., Larrieu, P., Moineaux, L., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colau, D., Wouters, J., Masereel, B., Van den Eynde, B. & Frédérick, R., 2011, p. Book of Abstracts, XVIIIème Journée Jeunes Chercheurs, 04/02/11, Paris, France. 1 p.

Research output: Contribution to conferencePoster

File
78 Downloads (Pure)

SYNTHESIS, ACTIVITY, CRYSTAL AND ELECTRONIC PROPERTIES OF ISOMERS OF CHLORO-PYRIDINYLVINYL-1H-INDOLES

Moineaux, L., Laurent, S., Dolusic, E., Reniers, J., Norberg, B., Frère, J-M., Galleni, M., Van den Eynde, B., Masereel, B., Frédérick, R. & Wouters, J., 2011, p. Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, P20, p. 45. 1 p.

Research output: Contribution to conferencePoster

Synthesis, structural, enzymatic and cellular studies of vinyl-1H-indole analogues as potential inhibitors of tryptophan 2,3-dioxygenase (TDO), an attractive target in cancer immunotherapy.

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Charlier, P., Laurent, S., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2011, p. Book of Abstracts, Annual One-Day Meeting on Medicinal Chemistry of SRC & KVCV (MedChem 2011), Ghent, 25 November 2011, p. 22. 1 p.

Research output: Contribution to conferencePoster

THIOSEMICARBAZONES AS INHIBITORS OF TRYPTOPHAN 2,3-DIOXYGENASE (TDO), AN EMERGING TARGET FOR CANCER TREATMENT

Dolusic, E., Modaffari, S., Larrieu, P., Vancraeynest, C., Pilotte, L., Colau, D., Stroobant, V., Van den Eynde, B., Wouters, J., Masereel, B. & Frédérick, R., 2011, p. Book of Abstracts, Annual One-Day Meeting on Medicinal Chemistry of SRC & KVCV (MedChem 2011), Ghent, 25 November 2011, p. 21. 1 p.

Research output: Contribution to conferencePoster

File
153 Downloads (Pure)

Tryptophan 2,3-dioxygenase (TDO) inhibitors : Identification of new scaffolds using virtual screening

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2011, p. Book of Abstracts, 25èmes Journées Franco-belges de Pharmacochimie, 19-20/05/11, Liège, p. 19. 1 p.

Research output: Contribution to conferencePoster

Open Access
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75 Downloads (Pure)
2010

Conception, synthèse et étude d'inhibiteurs de la tryptophane 2,3-dioxygénase (TDO), une cible prometteuse pour le traitement du cancer

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, p. Abstracts, Séminaire des jeunes chercheurs Télévie 2011, Brussels, Belgium, 7 December 2010. 1 p.

Research output: Contribution to conferencePoster

File
63 Downloads (Pure)

Design, synthesis and study of inhibitors of tryptophan 2,3-dioxygenase (TDO), a promising target for cancer therapy

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, p. Abstracts, école doctorale SFMBBM, Liège, Belgium, 10 December 2010. 1 p.

Research output: Contribution to conferencePoster

Discovery and Optimization Of Indole-pyridinyl-ethanones as Novel Inhibitors of Indoleamine-2,3-Dioxygenase (IDO), a Promising Target for Anti-Cancer Immunotherapy

Frédérick, R., Blanc, S., Larrieu, P., Moineaux, L., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colau, D., Wouters, J., Masereel, B., Van den Eynde, B. & Dolusic, E., 2010, p. PC.281, 21st ISMC, Brussels, Belgium, September 5-9, 2010, Drugs of the Future, volume 35, issue suppl. A, pp. 181-182. 2 p.

Research output: Contribution to conferencePoster

Indole-pyridinyl-ethanones as Novel Inhibitors of Indoleamine 2,3-Dioxygenase (IDO), a Promising Target forAnti-Cancer Immunotherapy

Dolusic, E., Blanc, S., Larrieu, P., Moineaux, L., Colette, D., Fraser, G., Stroobant, V., Pilotte, L., Colau, D., Wouters, J., Masereel, B., Van den Eynde, B. & Frédérick, R., 2010, p. Book of Abstracts, XXIVth European Colloquium on Heterocyclic Chemistry, Vienna, Austria, August 23-27, 2010. 1 p.

Research output: Contribution to conferencePoster

Open Access
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20 Downloads (Pure)

Synthesis, crystal and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, p. Abstracts, The sixth Belgian Crystallography Symposium (BCS-6), 13 October 2010, Brussels, Belgium. 1 p.

Research output: Contribution to conferencePoster

Tryptophan 2,3-dioxygenase (TDO) inhibitors : Identification of new scaffolds using virtual screening

Moineaux, L., Charlier, C., Dolusic, E., Larrieu, P., Pilotte, L., Colau, D., Stroobant, V., Galleni, M., Masereel, B., Van den Eynde, B., Wouters, J. & Frédérick, R., 2010, p. Abstracts, Journée scientifique de la Société royale de chimie (SRC), Gembloux, Belgium, 14 October 2010.

Research output: Contribution to conferencePoster

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37 Downloads (Pure)