Raphaël Frederick

  • 1152 Citations
  • 20 h-Index
20002018
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  • 13 Similar Profiles
Indoleamine-Pyrrole 2,3,-Dioxygenase Chemical Compounds
Tryptophan Oxygenase Medicine & Life Sciences
Derivatives Chemical Compounds
Monoamine Oxidase Medicine & Life Sciences
Coumarins Medicine & Life Sciences
Indoles Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Solubility Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2000 2013

Research Output 2001 2018

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting D-alanine-D-alanine ligase in bacterio

Ameryckx, A., Thabault, L., Pochet, L., Leimanis, S., Poupaert, J., Wouters, J., Joris, B., Van Bambeke, F. & Frederick, R., 5 Nov 2018, In : European journal of medicinal chemistry / Chimica therapeutica. 159, 5, p. 324-338 15 p.

Research output: Contribution to journalArticle

Open Access
Anti-Infective Agents
Cytotoxicity
Cells
Peptidoglycan
Structure-Activity Relationship

Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer

Brisson, L., Bański, P., Sboarina, M., Dethier, C., Danhier, P., Fontenille, M. J., Van Hée, V. F., Vazeille, T., Tardy, M., Falces, J., Bouzin, C., Porporato, P. E., Frédérick, R., Michiels, C., Copetti, T. & Sonveaux, P., 2016, In : Cancer Cell. 30, 3, p. 418-431 14 p.

Research output: Contribution to journalArticle

Autophagy
Lysosomes
Neoplasms
Lactic Acid
Glucose
Open Access
Harmine
Quantitative Structure-Activity Relationship
Solubility
Derivatives
Cells

Design of new small molecular weight inhibitors of FXIIa

Bouckaert, C., Serra, S., Dogne, J-M., Frederick, R. & Pochet, L., 4 Jun 2015.

Research output: Contribution to conferencePoster

Activities 1998 2007

  • 12 Participation in conference
  • 3 Participation in workshop, seminar, course

Discovery of new PI3K inhibitors using virtual screening Phosphoinositide-3-kinase (PI3Ks): combined comparative modeling and 3D-QSAR to rationalize the inhibition of p110alpha

Raphaël Frederick (Contributor)
3 Dec 2007

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

The Maurice Wilkins Centre for Molecular Biodiscovery Research Symposium

Raphaël Frederick (Contributor)
17 Aug 2007

Activity: Participating in or organising an event typesParticipation in conference

Post-Doc Stay at the "Auckland Cancer Society Research Centre" (University of Auckland, Auckland, New Zealand

Raphaël Frederick (Contributor)
5 Mar 20066 Nov 2007

Activity: Participating in or organising an event typesParticipation in conference

TRIPOS TRAINING WORKSHOP Ligand docking

Raphaël Frederick (Participant)
3 Mar 2006

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

TRIPOS TRAINING WORKSHOP Receptor-Ligand Modeling for New Modeller

Raphaël Frederick (Participant)
23 Feb 200624 Feb 2006

Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

Thesis

Conception, synthèse et étude d’inhibiteurs de la tryptophane 2,3-dioxygénase (TDO), une cible prometteuse pour le traitement du cancer

Author: Moineaux, L., 30 Jan 2012

Supervisor: Wouters, J. (Supervisor), Lanners, S. (President), Masereel, B. (Jury), Galleni, M. (External person) (Jury) & Frederick, R. (Jury)

Student thesis: Doc typesDoctor of Sciences

File

Conception, synthèse et évaluation biologique de coumarines en tant qu'inhibiteur de thrombine

Author: Frederick, R., 2003

Supervisor: Pochet, L. (Jury)

Student thesis: Master typesMaster in Pharmacy

Rational design, synthesis, molecular modeling and evaluation of β-carboline and 5H-indeno[1,2-c]pyridazin-5-one derivatives as potential MAO and IDO inhibitors

Author: Reniers, J., 4 Oct 2011

Supervisor: Wouters, J. (Supervisor), Frederick, R. (Jury), Michiels, C. (Jury), Vincent, S. (President) & Kiss, R. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

File

Synthèse de b-carbolines trisubstituées en tant que nouveaux agents antiprolifératifs

Author: Legrand, P., 2011

Supervisor: Frederick, R. (Supervisor)

Student thesis: Master typesMaster