Quentin THEMANS

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Projects

1 Finished
1 Active

Télévie: Design and enzymatic evaluation of new inhibitors of the serine metabolic pathway as potential anticancer agents : structural and functional approach of PHDGH

WOUTERS, J. & THEMANS, Q.

1/10/15 → …

Project: PHD

Crystallographic study of the mechanisms of inhibition of IDO and TDO enzymes through protein engineering: help in the design of mixed inhibitors as potential anticancer agents.

THEMANS, Q. & WOUTERS, J.

1/09/14 → 30/09/15

Project: Research

Research Output

10 Citations
2 h-Index
2 Article

Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation

Spillier, Q., Vertommen, D., Ravez, S., Marteau, R., Thémans, Q., Corbet, C., Feron, O., Wouters, J. & Frédérick, R., 18 Mar 2019, In : Scientific Reports. 9, 1, 4737.

Research output: Contribution to journal › Article

Open Access

Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase

Balti, M., Plas, A., Meinguet, C., Haufroid, M., Thémans, Q., Efrit, M. L., Wouters, J. & Lanners, S., 1 Aug 2017, In : Bioorganic and medicinal chemistry letters. 27, 15, p. 3607-3610 4 p.

Research output: Contribution to journal › Article

Activities

9 Participation in conference
1 Participation in workshop, seminar, course

PhD Student Day 2015-2016

Quentin Themans (Participant)

20 May 2016

Activity: Participating in or organising an event types › Participation in conference

Séminaire des chercheurs Télévie

Quentin Themans (Participant)

3 Dec 2015

Activity: Participating in or organising an event types › Participation in conference

8 th Annual meeting of the SFMBBM doctoral school

Quentin Themans (Poster)

14 Nov 2015

Activity: Participating in or organising an event types › Participation in conference

Winter School Protéomique

Quentin Themans (Participant)

16 Nov 2015 → 20 Nov 2015

Activity: Participating in or organising an event types › Participation in workshop, seminar, course

Journée scientifique de la société Royale de Chimie (SRC)

Quentin Themans (Poster)

8 Oct 2015

Activity: Participating in or organising an event types › Participation in conference

Thesis

Approche structurale et fonctionnelle de la première enzyme de la voie de la sérine: PHGDH, une cible potentielle pour le traitement du cancer

Author: Themans, Q., 18 Oct 2019

Supervisor: Wouters, J. (Supervisor), Leherte, L. (President), Unterlass, J. (External person) (Jury), Sirigu, S. (External person) (Jury) & Röhrig, U. (External person) (Jury)

Student thesis: Doc types › Doctor of Sciences

File

Conception de composés anti-cancéreux ciblant le domaine PWWP des DNMT3A et DNMT3B

Author: Themans, Q., 2014

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master types › Master in Chemistry