Pierre Van Durm

  • 61 Citations
  • 4 h-Index
20072013
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Research Output 2009 2013

  • 61 Citations
  • 4 h-Index
  • 5 Article
2013

Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials

Verbrugghen, T., Van Calenbergh, S., Vandurm, P., Pouyez, J., Wouters, J. & Maes, L., 10 Jan 2013, In : Journal of Medicinal Chemistry. 56, 1, p. 376-380 5 p.

Research output: Contribution to journalArticle

Antimalarials
Plasmodium falciparum
Organophosphonates
Triazoles
Amides
2011
Bearings (structural)
HIV Integrase Inhibitors
Integrase Inhibitors
Integrases
Molecular modeling
2010
Crystal structure
Enzymes
Aspartic Acid
Catalytic Domain
Salts
2009
Integrase Inhibitors
human immunodeficiency virus
tautomers
Quinolones
inhibitors

Structural and theoretical studies of [6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)]-4-hydroxy-2-oxo-3-butenoïc acid as HIV-1 integrase inhibitor

Vandurm, P., Cauvin, C., Guiguen, A., Georges, B., Van, K. L., Martinelli, V., Cardona, C., Mbemba, G., Mouscadet, J. F., Hevesi, L., Lint, C. V. & Wouters, J., 15 Aug 2009, In : Bioorganic & Medicinal Chemistry Letters. 19, 16, p. 4806-4809 4 p.

Research output: Contribution to journalArticle

HIV Integrase Inhibitors
Integrase Inhibitors
Quinolones
Dihedral angle
Structure-Activity Relationship