Pierre Van Durm

  • 61 Citations
  • 4 h-Index
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  • 38 Similar Profiles
Integrase Inhibitors Chemical Compounds
Quinolones Chemical Compounds
HIV Integrase Inhibitors Medicine & Life Sciences
Acids Chemical Compounds
Antiviral Agents Chemical Compounds
Bearings (structural) Chemical Compounds
Integrases Chemical Compounds
Molecular modeling Chemical Compounds

Projects 2007 2011

titre en anglais

Wouters, J. & Van Durm, P.


Project: PHD

Research Output 2009 2013

  • 61 Citations
  • 4 h-Index
  • 5 Article

Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials

Verbrugghen, T., Van Calenbergh, S., Vandurm, P., Pouyez, J., Wouters, J. & Maes, L., 10 Jan 2013, In : Journal of Medicinal Chemistry. 56, 1, p. 376-380 5 p.

Research output: Contribution to journalArticle

Plasmodium falciparum
Bearings (structural)
HIV Integrase Inhibitors
Integrase Inhibitors
Molecular modeling
Crystal structure
Aspartic Acid
Catalytic Domain
Integrase Inhibitors
human immunodeficiency virus

Structural and theoretical studies of [6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)]-4-hydroxy-2-oxo-3-butenoïc acid as HIV-1 integrase inhibitor

Vandurm, P., Cauvin, C., Guiguen, A., Georges, B., Van, K. L., Martinelli, V., Cardona, C., Mbemba, G., Mouscadet, J. F., Hevesi, L., Lint, C. V. & Wouters, J., 15 Aug 2009, In : Bioorganic & Medicinal Chemistry Letters. 19, 16, p. 4806-4809 4 p.

Research output: Contribution to journalArticle

HIV Integrase Inhibitors
Integrase Inhibitors
Dihedral angle
Structure-Activity Relationship


Conception d'inhibiteurs de l'intégrase du VIH-1 dérivés du cycle quinolone

Author: Vandurm, P., 2007

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master typesMaster in Chemistry

Structural study of HIV-1 integrase inhibition by quinolones: contribution to the rational design of new inhibitors

Author: Vandurm, P., 3 Oct 2011

Supervisor: Wouters, J. (Supervisor), Masereel, B. (Jury), De Bolle, X. (Jury), Bonifazi, D. (President) & Mouscadet, J. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences