Pierre Van Durm

  • 58 Citations
  • 4 h-Index
20072013
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  • 39 Similar Profiles
Integrase Inhibitors Chemical Compounds
Quinolones Chemical Compounds
HIV Integrase Inhibitors Medicine & Life Sciences
Acids Chemical Compounds
Antiviral Agents Chemical Compounds
Bearings (structural) Chemical Compounds
Integrases Chemical Compounds
Molecular modeling Chemical Compounds

Projects 2007 2011

titre en anglais

Wouters, J. & Van Durm, P.

1/10/0730/09/11

Project: PHD

Research Output 2009 2013

  • 58 Citations
  • 4 h-Index
  • 5 Article

Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials

Verbrugghen, T., Van Calenbergh, S., Vandurm, P., Pouyez, J., Wouters, J. & Maes, L., 10 Jan 2013, In : Journal of Medicinal Chemistry. 56, 1, p. 376-380 5 p.

Research output: Contribution to journalArticle

Antimalarials
Plasmodium falciparum
Organophosphonates
Triazoles
Amides
Bearings (structural)
HIV Integrase Inhibitors
Integrase Inhibitors
Integrases
Molecular modeling
Crystal structure
Enzymes
Aspartic Acid
Catalytic Domain
Salts
Integrase Inhibitors
human immunodeficiency virus
tautomers
Quinolones
inhibitors

Structural and theoretical studies of [6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)]-4-hydroxy-2-oxo-3-butenoïc acid as HIV-1 integrase inhibitor

Vandurm, P., Cauvin, C., Guiguen, A., Georges, B., Van, K. L., Martinelli, V., Cardona, C., Mbemba, G., Mouscadet, J. F., Hevesi, L., Lint, C. V. & Wouters, J., 15 Aug 2009, In : Bioorganic & Medicinal Chemistry Letters. 19, 16, p. 4806-4809 4 p.

Research output: Contribution to journalArticle

HIV Integrase Inhibitors
Integrase Inhibitors
Quinolones
Dihedral angle
Structure-Activity Relationship

Thesis

Conception d'inhibiteurs de l'intégrase du VIH-1 dérivés du cycle quinolone

Author: Vandurm, P., 2007

Supervisor: Wouters, J. (Supervisor)

Student thesis: Master typesMaster in Chemistry

Structural study of HIV-1 integrase inhibition by quinolones: contribution to the rational design of new inhibitors

Author: Vandurm, P., 3 Oct 2011

Supervisor: Wouters, J. (Supervisor), Masereel, B. (Jury), De Bolle, X. (Jury), Bonifazi, D. (President) & Mouscadet, J. (External person) (Jury)

Student thesis: Doc typesDoctor of Sciences

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