Projects per year
Personal profile
Introduction
Assistant Professor, teaching General and Organ Histology at the Faculty of Medicine and Faculty of Sciences.
Group Leader at LNR - Laboratoire Neurodégénérescence et Régénération, member of URPhyM Research Unit and NARILIS.
Our activities are focused on the role of glial cells and glutamate transporters in CNS disorders such as osmotic demyelination syndrome (ODS) and spinal cord injuries.
Areas of expertise
Neurosciences
Neurodegenerative disorders : ALS, AD
CNS trauma : SCI
iPS, neural stem cell and glial precursor biology
Cell therapy
Neurosurgery on small animals
External responsibilities
Co-director of PFT Morph-IM (2017 - ...)
Member of the Board of B.S.C.D.B.
Member of the Belgian Society for Neuroscience
Member of the Board of Belgian Brain Council
Reviewer for F.R.S./F.N.R.S. and F.W.O.
Diplomas
2013 - Post-doctoral fellowship (CMMI, Erasme Hospital, Brussels, Belgium)
2011 - Post-doctoral fellowship (Thomas Jefferson University, Philadelphia, USA)
2010 - PhD Thesis (Université Libre de Bruxelles, Belgium)
2002 - MSc in Biomedical Sciences (Université Libre de Bruxelles, Belgium)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of the University, This work was aimed at developing effective strategies for amyotrophic lateral sclerosis (ALS) repair using neural precursor cell transplantation (derived from adult neural stem cells or human induced-pluripotent stem cells) and characterizing the blood-brain barrier of the SOD1G93A rat model of ALS., Université Libre de Bruxelles
Award Date: 30 Jun 2010
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Plateforme technologique d’excellence interuniversitaire sur les méthodes alternatives à l'expérimentation animale - Exercice budgétaire 2024
Poumay, Y. (PI), Nicaise, C. (PI) & Renard, H. F. (PI)
1/01/24 → 31/12/24
Project: Research
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From the identification of pathogenic autoantibodies in patients with neurological post-acute sequelae of COVID-19 to mechanisms of neuronal-derived neoantigen production
Mignolet, M. (PI), Nicaise, C. (Supervisor) & Gillet, N. (CoI)
1/10/23 → 31/12/25
Project: Research
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Development of 3D-brain organoids in the context of SARS-CoV-2 infection
Mignolet, M. (PI) & Nicaise, C. (PI)
16/01/23 → …
Project: Research
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From the identification of pathogenic autoantibodies in patients with neurological post-acute sequelae of COVID-19 to mechanisms of neuronal-derived neoantigen production
Mignolet, M. (Researcher), Nicaise, C. (Supervisor) & Gillet, N. (Co-supervisor)
16/01/23 → …
Project: PHD
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Développement de motoneurones phréniques à partir de cellules souches pluripotentes induites
Halloin, N. (PI) & Nicaise, C. (PI)
1/02/22 → …
Project: Research
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Lesion Extension and Neuronal Loss after Spinal Cord Injury Using X-Ray Phase-Contrast Tomography in Mice
Maugeri, L., Jankovski, A., Malucelli, E., Mangini, F., Vandeweerd, J. M., Gilloteaux, J., De Swert, K., Brun, F., Begani Provinciali, G., Dinuzzo, M., Mittone, A., Bravin, A., Gigli, G., Giove, F., Cedola, A., Nicaise, C. & Fratini, M., 1 May 2023, In: Journal of neurotrauma. 40, 9-10, p. 939-951 13 p.Research output: Contribution to journal › Article › peer-review
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Loss of Ephaptic Contacts in the Murine Thalamus during Osmotic Demyelination Syndrome
Gilloteaux, J., De Swert, K., Suain, V., Brion, J. P. & Nicaise, C., 2023, In: Ultrastructural Pathology. 47, 5, p. 398-423 26 p.Research output: Contribution to journal › Article › peer-review
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Neurofilament accumulations in amyotrophic lateral sclerosis patients’ motor neurons impair axonal initial segment integrity
Lefebvre-Omar, C., Liu, E., Dalle, C., d’Incamps, B. L., Bigou, S., Daube, C., Karpf, L., Davenne, M., Robil, N., Jost Mousseau, C., Blanchard, S., Tournaire, G., Nicaise, C., Salachas, F., Lacomblez, L., Seilhean, D., Lobsiger, C. S., Millecamps, S., Boillée, S. & Bohl, D., Jun 2023, In: Cellular and Molecular Life Sciences. 80, 6, 150.Research output: Contribution to journal › Article › peer-review
Open Access -
Thalamic Neuron Resilience during Osmotic Demyelination Syndrome (ODS) Is Revealed by Primary Cilium Outgrowth and ADP-ribosylation factor-like protein 13B Labeling in Axon Initial Segment
Gilloteaux, J., De Swert, K., Suain, V. & Nicaise, C., 17 Nov 2023, In: International Journal of Molecular Sciences. 24, 22, 16448.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Downloads (Pure) -
Viral entry inhibitors protect against SARS-CoV-2-induced neurite shortening in differentiated SH-SY5Y cells
MIGNOLET, M., Gilloteaux, J., Halloin, N., Gueibe, M., Willemart, K., De Swert, K., Bielarz, V., Suain, V., Pastushenko, I., Gillet, N. & Nicaise, C., Oct 2023, In: Viruses. 15, 10, 2020.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Downloads (Pure)
Datasets
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Viral entry inhibitors protect against SARS-CoV-2-induced neurite shortening in differentiated SH-SY5Y cells
Nicaise, C. (Creator), MIGNOLET, M. (Creator), GILLOTEAUX, J. (Creator) & Gueibe, M. (Creator), University of Namur, 24 Aug 2023
Dataset
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The cystine/glutamate xCT antiporter: yet another glial glutamate transporter modulating recovery following spinal cord injury?
Nicaise, C. (Speaker)
21 May 2022Activity: Talk or presentation types › Invited talk
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Role of Cystine/glutamate antiporter in the spinal cord
Nicaise, C. (Speaker)
13 Mar 2022Activity: Talk or presentation types › Invited talk
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Non coding RNA in health and disease
Nicaise, C. (Organiser), Renard, P. (Organiser), Muylkens, B. (Organiser), Lafontaine, D. L. J. (Organiser) & Van Scherpenzeel Thim, V. (Organiser)
18 Mar 2022Activity: Participating in or organising an event types › Participation to a Symposium, a study Day
Press/Media
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New Findings Reported from Universite de Namur Describe Advances in COVID-19 (Viral Entry Inhibitors Protect against SARS-CoV-2-Induced Neurite Shortening in Differentiated SH-SY5Y Cells)
Nicaise, C., GILLOTEAUX, J., Bielarz, V., De Swert, K. & Gillet, N.
9/11/23
1 item of Media coverage
Press/Media: Expert Comment
Equipment
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Histology platform
Nicaise, C. (Manager), Poumay, Y. (Manager) & Bielarz, V. (Other)
Technological Platform Morphology - ImagingFacility/equipment: Equipment