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Dive into the research topics where Manon Mirgaux is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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Projects
- 2 Finished
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Towards the design of innovating inhibitors for the first step of the kynurenine pathway
Mirgaux, M. (PI) & Wouters, J. (Supervisor)
1/10/21 → 30/09/23
Project: Research
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Cancer immunotherapy and dual IDO/TDO inhibitors: design, synthesis, physico-chemical and biological characterizations
Mirgaux, M. (PI) & Wouters, J. (Supervisor)
1/10/19 → 30/09/21
Project: Research
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Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family
Megalizzi, V., Tanina, A., Grosse, C., Mirgaux, M., Legrand, P., Dias Mirandela, G., Wohlkönig, A., Bifani, P. & Wintjens, R., 30 Nov 2024, In: Heliyon. 10, 22, e40494.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Downloads (Pure) -
Human indoleamine-2,3-dioxygenase 2 cofactor lability and low substrate affinity explained by homology modeling, molecular dynamics and molecular docking
Mirgaux, M., Leherte, L. & Wouters, J., 2023, In: Journal of Biomolecular Structure & Dynamics. 42, 9, p. 4475-4488 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile61 Downloads (Pure) -
Structural study of bioisosteric derivatives of 5-(1 H-indol-3-yl)-benzotriazole and their ability to form chalcogen bonds
Mirgaux, M., Scaillet, T., Kozlova, A., Tumanov, N., Frédérick, R., Bodart, L. & Wouters, J., 1 Apr 2022, In: Acta Crystallographica. Section E: Crystallographic Communications. 78, 4, p. 418-424 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Downloads (Pure) -
Temporary Intermediates of L-Trp Along the Reaction Pathway of human Indoleamine 2,3-dioxygenase 1 and Identification of an Exo Site
Mirgaux, M., Leherte, L. & Wouters, J., 15 Dec 2021, In: International Journal of Tryptophan Research. 14, p. 1- 11Research output: Contribution to journal › Article › peer-review
Open AccessFile79 Downloads (Pure) -
Influence of the presence of the heme cofactor on the JK-loop structure in indoleamine-2,3-dioxygenase-1
Mirgaux, M., Leherte, L. & Wouters, J., 1 Dec 2020, In: Acta crystallographica. Section D: Structural Biology. 76, p. 1211-1221Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Downloads (Pure)
Datasets
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Crystal structure of L-Trp/Indoleamine 2,3-dioxygenase (hIDO1) complex with the JK-loop refined in the intermediate conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7P0R/pdb
Dataset
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Human phosphoserine phosphatase with serine and phosphate
Wouters, J. (Creator), Haufroid, M. (Creator) & MIRGAUX, M. (Creator), University of Namur, 12 Jun 2019
DOI: 10.2210/pdb6HYY/pdb
Dataset
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Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the open conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7P0N/pdb
Dataset
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Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the closed conformation
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 29 Dec 2021
DOI: 10.2210/pdb7NGE/pdb
Dataset
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Structure of human indoleamine-2,3-dioxygenase 1 (hIDO1) with a complete JK loop
MIRGAUX, M. (Creator) & Wouters, J. (Creator), University of Namur, 16 Dec 2020
DOI: 10.2210/pdb7A62/pdb
Dataset
Prizes
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Mechanistic study of the human phosphoserine phosphatase (hPSP): crystallographic and computational approaches
MIRGAUX, M. (Recipient), 10 Oct 2019
Prize: Prize (including medals and awards)
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Mechanistic study of the human phosphoserine phosphatase (hPSP): crystallographic and computational approaches
MIRGAUX, M. (Recipient), 15 Nov 2019
Prize: Prize (including medals and awards)
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Young Medicinal Chemist Award in Belgium (SRC)
MIRGAUX, M. (Recipient), 19 May 2022
Prize: Prize (including medals and awards)
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9th EFMC Young Medicinal Chemists' Symposium
MIRGAUX, M. (Contributor)
9 Sept 2022Activity: Participating in or organising an event types › Participation in conference
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33rd European Crystallography Meeting
MIRGAUX, M. (Poster)
23 Aug 2022 → 27 Aug 2022Activity: Participating in or organising an event types › Participation in conference
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3rd FNRS Med Chem Symposium
MIRGAUX, M. (Contributor)
19 May 2022Activity: Participating in or organising an event types › Participation in conference
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Women and Girls in Science
MIRGAUX, M. (Poster)
27 Apr 2022 → 28 Apr 2022Activity: Participating in or organising an event types › Participation in conference
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Journée-Rencontre des Jeunes Chimistes
MIRGAUX, M. (Contributor)
1 Apr 2022Activity: Participating in or organising an event types › Participation in conference
Thesis
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Étude mécanistique de la phosphosérine phosphatase humaine, une enzyme impliquée dans la chimiorésistance au 5-Fluorouracile dans le cancer du côlon : approches expérimentale et computationnelle
Mirgaux, M. (Author), Wouters, J. (Supervisor) & Champagne, B. (Co-Supervisor), Jun 2019Student thesis: Master types › Master in Chemistry Research focus
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Plasticity of human indoleamine-2,3-dioxygenases 1 and 2 through a structural approach combining crystallography and Molecular Dynamics studies
MIRGAUX, M. (Author), Wouters, J. (Supervisor), Olivier, Y. (President), Leherte, L. (Jury), Labar, G. (Jury), Röhrig, U. (Jury) & Wintjens, R. (Jury), 16 Nov 2022Student thesis: Doc types › Doctor of Sciences
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