Projects per year
Personal profile
Areas of expertise
Protein chemistry, structural physical chemistry, structural biology, biophysics, intrinsically disordered proteins (IDPs), aggregation, amyloid fibrils, protein-protein interactions (PPIs).
Diplomas
Bachelor in chemistry (University of Namur, 2019)
Master 120 in chemistry, research focus (University of Namur, 2021)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Unravelling the disorder-aggregation-properties relationships of the intrinsically disordered protein DPF3: towards new antimitotic strategies
Mignon, J. (PI) & Michaux, C. (Supervisor)
1/10/24 → 30/09/26
Project: Research
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Unravelling the disorder-aggregation-properties relationships of the intrinsically disordered protein DPF3: towards new antimitotic strategies
Mignon, J. (PI) & Michaux, C. (Supervisor)
1/10/22 → 30/09/24
Project: Research
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Fuzzy complexes
Mignon, J., Leyder, T. & Michaux, C., 1 Jan 2024, The Three Functional States of Proteins: Structured, Intrinsically Disordered, and Phase Separated. Tripathi, T. & Uversky, V. N. (eds.). Academic Press, p. 123-143 21 p.Research output: Contribution in Book/Catalog/Report/Conference proceeding › Chapter
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In-depth investigation of the effect of pH on the autofluorescence properties of DPF3b and DPF3a amyloid fibrils
Mignon, J., Leyder, T., Mottet, D., Uversky, V. N. & Michaux, C., 15 May 2024, In: Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy. 313, 20 p., 124156.Research output: Contribution to journal › Article › peer-review
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Intrinsic disorder and salt-dependent conformational changes of the N-terminal region of TFIP11 splicing factor
Juniku, B., Mignon, J., Carême, R., Genco, A., Obeid, A. M., Mottet, D., Monari, A. & Michaux, C., Oct 2024, In: International journal of biological macromolecules. 277, 3, 134291.Research output: Contribution to journal › Article › peer-review
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Non-canonical role for the BAF complex subunit DPF3 in mitosis and ciliogenesis
Verrillo, G., Obeid, A. M., Genco, A., Scrofani, J., Orange, F., Hanache, S., Mignon, J., Leyder, T., Michaux, C., Kempeneers, C., Bricmont, N., Herkenne, S., Vernos, I., Martin, M. & Mottet, D., May 2024, In: Journal of Cell Science. 137, 9Research output: Contribution to journal › Article › peer-review
Open Access -
Structural characterisation of amyloidogenic intrinsically disordered zinc finger protein isoforms DPF3b and DPF3a
Mignon, J., Mottet, D., Leyder, T., Uversky, V. N., Perpete, E. & Michaux, C., 1 Oct 2022, In: International journal of biological macromolecules. 218, p. 57-71 15 p.Research output: Contribution to journal › Article › peer-review
Prizes
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Prix du meilleur mémoire de master en sciences chimiques de l'Université de Namur
Mignon, J. (Recipient), 2021
Prize: Prize (including medals and awards)
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Prize of the best scientific poster (EFID 2022)
Mignon, J. (Recipient), Jun 2022
Prize: Prize (including medals and awards)
Thesis
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Caractérisation des interactions protéine-protéine dans le complexe DPF3-PLK1 impliqué dans la mitose cellulaire
Mignon, J. (Author), Michaux, C. (Supervisor) & Perpete, E. (Co-Supervisor), 2021Student thesis: Master types › Master in Chemistry Research focus
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