Research Output 1984 2018

  • 2003 Citations
  • 20 h-Index
  • 69 Article
  • 2 Poster
  • 1 Comment/debate
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Article
2018
File
Lipolysis
Autophagy
Adipocytes
Triglycerides
Mitochondria
2017
Neutral Amino Acid Transport Systems
Glutamine
Sodium
Growth
Neoplasms
2016

Accounting for protein subcellular localization: A compartmental map of the rat liver proteome

Jadot, M., Boonen, M., Thirion, J., Wang, N., Xing, J., Zhao, C., Tannous, A., Qian, M., Zheng, H., Everett, J. K., Moore, D. F., Sleat, D. E. & Lobel, P. 2016 In : Molecular & cellular proteomics : MCP.

Research output: Contribution to journalArticle

Open Access
File
Proteome
Liver
Proteins
Rats
Organelles
Golgi Apparatus
Endoplasmic Reticulum
Glycine
Proteins
Autophagy

Cathepsin D and its newly identified transport receptor SEZ6L2 can modulate neurite outgrowth

Boonen, M., Staudt, C., Gilis, F., Oorschot, V., Klumperman, J. & Jadot, M. 2016 In : Journal of Cell Science. 129, 3, p. 557-68 12 p.

Research output: Contribution to journalArticle

Cathepsin D
Neuronal Outgrowth
Endosomes
Brain
mannose-6-phosphate
Golgi Apparatus
Endoplasmic Reticulum
Human Trafficking
trans-Golgi Network
Sequence Deletion
2015

The Na+/K+-ATPase and the amyloid-beta peptide aβ1-40 control the cellular distribution, abundance and activity of TRPC6 channels

Chauvet, S., Boonen, M., Chevallet, M., Jarvis, L., Abebe, A., Benharouga, M., Faller, P., Jadot, M. & Bouron, A. 1 Nov 2015 In : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 11, p. 2957-2965 9 p., 17657

Research output: Contribution to journalArticle

Amyloid beta-Peptides
Ouabain
Adenosine Triphosphatases
sodium-translocating ATPase
Peptides
2014
Lysosomes
Liver
Proteins
Hyaluronic Acid
Hyaluronoglucosaminidase
Open Access
File
Brucella melitensis
Brucella abortus
Autophagy
Fibroblasts
Brucella
Hydrolases
Macrophages
Endosomes
Hyaluronic Acid
Proteins
2013
Open Access
File
Sterols
Sucrose
Carrier Proteins
Sterol Regulatory Element Binding Proteins
Transcription Factors

An extended proteome map of the lysosomal membrane reveals novel potential transporters

Chapel, A., Kieffer-Jaquinod, S., Sagné, C., Verdon, Q., Ivaldi, C., Mellal, M., Thirion, J., Jadot, M., Bruley, C., Garin, J., Gasnier, B. & Journet, A. 1 Jun 2013 In : Molecular and Cellular Proteomics. 12, 6, p. 1572-1588 17 p.

Research output: Contribution to journalArticle

Proteome
Lysosomes
Membranes
Proteins
lysosomal proteins
Open Access
File
Ceroid
Oxidative stress
Fibroblasts
Proteins
tripeptidyl-peptidase 1
2012

Lipids and lysosomes

Hamer, I., Van Beersel, G., Arnould, T. & Jadot, M. 1 Dec 2012 In : Current Drug and Metabolism. 13, 10, p. 1371-1387 17 p.

Research output: Contribution to journalArticle

Lysosomes
Lipids
Membranes
Macromolecules
Enzymes
2011

Classification of subcellular location by comparative proteomic analysis of native and density-shifted lysosomes

Della Valle, M. C., Sleat, D. E., Zheng, H., Moore, D. F., Jadot, M. & Lobel, P. 1 Apr 2011 In : Molecular and Cellular Proteomics. 10, 4

Research output: Contribution to journalArticle

Lysosomes
Proteomics
Proteins
Organelles
Adenosine Triphosphate

Hyal2 is a glycosylphosphatidylinositol-anchored, lipid raft-associated hyaluronidase

Andre, B., Duterme, C., Van Moer, K., Mertens-Strijthagen, J., Jadot, M. & Flamion, B. 22 Jul 2011 In : Biochemical and Biophysical Research Communications. 411, 1, p. 175-179 5 p.

Research output: Contribution to journalArticle

Glycosylphosphatidylinositols
Hyaluronoglucosaminidase
Lipids
Membranes
Hyaluronic Acid

Loss of niemann-pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway

Dixit, S. S., Jadot, M., Sohar, I., Sleat, D. E., Stock, A. M. & Lobel, P. 24 Aug 2011 In : PLoS ONE. 6, 8

Research output: Contribution to journalArticle

cholesterol
proteins
Proteins
lysosomes
Lysosomes
2010

Endocytosis of hyaluronidase-1 by the liver

Gasingirwa, M-C., Thirion, J., Mertens-Strijthagen, J., Wattiaux-De Coninck, S., Flamion, B., Wattiaux, R. & Jadot, M. 1 Sep 2010 In : Biochemical Journal. 430, 2, p. 305-313 9 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Endocytosis
Liver
Enzymes
Centrifugation
Neuronal Ceroid-Lipofuscinoses
Lysosomal Storage Diseases
Glial Fibrillary Acidic Protein
Ceroid
Proteins
2009
Cathepsin B
Osteosarcoma
Mitochondrial DNA
Up-Regulation
Oxidative Phosphorylation
2008

Acid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteins

Sun, P., Sleat, D. E., Lecocq, M., Hayman, A. R., Jadot, M. & Lobel, P. 28 Oct 2008 In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16590-16595 6 p.

Research output: Contribution to journalArticle

Acid Phosphatase
lysosomal proteins
mannose-6-phosphate
Lysosomes
Enzymes
Open Access
File
Lysosome-Associated Membrane Glycoproteins
Lysosomes
adjuvant P40
trans-Golgi Network
Leucine

A method to assess the lysosomal residence of proteins in cultured cells

Gasingirwa, M. C., Thirion, J., Costa, C., Flamion, B., Lobel, P. & Jadot, M. 1 Mar 2008 In : Analytical Biochemistry. 374, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

Progesterone
Cells
lysosomal proteins
Lysosomes
Cultured Cells
2007

Biochemical characterization and lysosomal localization of the mannose-6-phosphate protein p76 (hypothetical protein LOC196463)

Jensen, A. G., Chemali, M., Chapel, A., Kieffer-Jaquinod, S., Jadot, M., Garin, J. & Journet, A. 15 Mar 2007 In : Biochemical Journal. 402, 3, p. 449-458 10 p.

Research output: Contribution to journalArticle

Proteins
mannose-6-phosphate
lysosomal proteins
Proteomics
Experiments

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

Nielsen, R., Courtoy, P. J., Jacobsen, C., Dom, G., Lima, W. R., Jadot, M., Willnow, T. E., Devuyst, O. & Christensen, E. I. 27 Mar 2007 In : Proceedings of the National Academy of Sciences of the United States of America. 104, 13, p. 5407-5412 6 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-2
Cathepsin B
Endocytosis
Kidney
Lysosomes

Lysosomal proteomics and disease

Sleat, D. E., Jadot, M. & Lobel, P. 1 Sep 2007 In : Proteomics - Clinical Applications. 1, 9, p. 1134-1146 13 p.

Research output: Contribution to journalArticle

Proteomics
Organelles
Lysosomes
Macromolecular Substances
Inborn Genetic Diseases

Lysosomes and Fas-mediated liver cell death

Wattiaux, R., Wattiaux-De Coninck, S., Thirion, J., Gasingirwa, M. C. & Jadot, M. 1 Apr 2007 In : Biochemical Journal. 403, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Cell death
Liver
Apoptosis
Antibodies
Enzymes
2006

Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method

Della Valle, M. C., Sleat, D. E., Sohar, I., Wen, T., Pintar, J. E., Jadot, M. & Lobel, P. 17 Nov 2006 In : Journal of Biological Chemistry. 281, 46, p. 35436-35445 10 p.

Research output: Contribution to journalArticle

Demonstrations
Proteins
ependymins
mannose-6-phosphate
lysosomal proteins

Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes

Boonen, M., Hamer, I., Boussac, M., Delsaute, A. F., Flamion, B., Garin, J. & Jadot, M. 1 Apr 2006 In : Biochemical Journal. 395, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Membranes
Proteins
adjuvant P40
Lysosomes
Lysosome-Associated Membrane Glycoproteins
2005

Endolysosomal transport of newly-synthesized cathepsin D in a sucrose model of lysosomal storage

Hamer, I. & Jadot, M. 1 Oct 2005 In : Experimental Cell Research. 309, 2, p. 284-295 12 p.

Research output: Contribution to journalArticle

Cathepsin D
Organelles
Sucrose
Hydrolases
Lysosomes
2004

Calcium entry into keratinocytes induces exocytosis of lysosomes

Jans, R., Sartor, M., Jadot, M. & Poumay, Y. 1 Jun 2004 In : Archives of Dermatological Research. 296, 1, p. 30-41 12 p.

Research output: Contribution to journalArticle

Open Access
File
Ionomycin
Exocytosis
Lysosomes
Keratinocytes
Calcium
Keratinocytes
Up-Regulation
Cholesterol
involucrin
Chemical activation
Hydrodynamics
Transfection
Hepatocytes
Injections
Liver
2003
Cathepsin C
Giardia lamblia
Trophozoites
Acid Phosphatase
Organelles
Tail
Veins
Plasmids
Injections
Liver
2002

Importance of the propeptide in the biosynthetic maturation of rat cathepsin C

Santilman, V., Jadot, M. & Mainferme, F. 1 Dec 2002 In : European journal of cell biology. 81, 12, p. 654-663 10 p.

Research output: Contribution to journalArticle

Cathepsin C
Glycosylation
Enzymes
Lysosomes
Tryptophan

Uptake and intracellular fate of gelonin, a ribosome-inactivating protein, in rat liver

Colaço, M., Bapat, M. M., Misquith, S., Jadot, M., Wattiaux-De Coninck, S. & Wattiaux, R. 14 Oct 2002 In : Biochemical and Biophysical Research Communications. 296, 5, p. 1180-1185 6 p.

Research output: Contribution to journalArticle

Ribosome Inactivating Proteins
Liver
Rats
Gelonium multiflorum GEL protein
Radioactivity
2001

Effects of methylcyclodextrin on lysosomes

Jadot, M., Andrianaivo, F., Dubois, F. & Wattiaux, R. 2 Apr 2001 In : European Journal of Biochemistry . 268, 5, p. 1392-1399 8 p.

Research output: Contribution to journalArticle

Cyclodextrins
Lysosomes
Membranes
Centrifugation
Sucrose
2000

Endosomes, lysosomes: Their implication in gene transfer

Wattiaux, R., Laurent, N., Wattiaux-De Coninck, S. & Jadot, M. 30 Mar 2000 In : Advanced Drug Delivery Reviews. 41, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

Endosomes
Lysosomes
DNA
Genes
Plasmids

Identification of HE1 as the second gene of Niemann-Pick C disease

Naureckiene, S., Sleat, D. E., Lacklan, H., Fensom, A., Vanier, M. T., Wattiaux, R., Jadot, M. & Lobel, P. 22 Dec 2000 In : Science. 290, 5500, p. 2298-2301 4 p.

Research output: Contribution to journalArticle

Niemann-Pick Diseases
Fibroblasts
Genes
Lysosomes
Recombinant Proteins
Polyethyleneimine
Lysosomes
Radioactivity
Polyamines
Hydrolases
1999
Ceroid
Assays
Animals
Peptide Hydrolases
Enzymes

Subcellular localization of mannose 6-phosphate glycoproteins in rat brain

Jadot, M., Lin, L., Sleat, D. E., Sohar, I., Hsu, M. S., Pintar, J., Dubois, F., Wattiaux-de Coninck, S., Wattiaux, R. & Lobel, P. 23 Jul 1999 In : Journal of Biological Chemistry. 274, 30, p. 21104-21113 10 p.

Research output: Contribution to journalArticle

Rats
Brain
Glycoproteins
mannose-6-phosphate
Enzymes

Uptake by rat liver and intracellular fate of plasmid DNA complexed with poly-L-lysine or poly-D-lysine

Laurent, N., Wattiaux-De Coninck, S., Mihaylova, E., Leontieva, E., Warnier-Pirotte, M. T., Wattiaux, R. & Jadot, M. 22 Jan 1999 In : FEBS Letters. 443, 1, p. 61-65 5 p.

Research output: Contribution to journalArticle

Liver
Lysine
Rats
Plasmids
DNA
1998

Expression of Lamp-1 and Lamp-2 and their interactions with galectin-3 in human tumor cells

Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J-J., Van den Brule, F., Castrunovo, V., Wattiaux, R. & Wattiaux-De Coninck, S. 5 Jan 1998 In : International Journal of Cancer. 75, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

Galactosides
Lectins
Neoplasms
Lysosome-Associated Membrane Glycoproteins
Glycoproteins

ΔF508 CFTR localizes in the endoplasmic reticulum - Golgi intermediate compartment in cystic fibrosis cells

Gilbert, A., Jadot, M., Leontieva, E., Wattiaux-De Coninck, S. & Wattiaux, R. 10 Jul 1998 In : Experimental Cell Research. 242, 1, p. 144-152 9 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Endoplasmic Reticulum
Proteins
Calnexin
Iohexol
1997

Biological functions of lysosomal membrane-associated glycoproteins

Sarafian, V., Jadot, M., Wattiaux-De Coninck, S. & Wattiaux, R. 1 Jan 1997 In : Biomedical Reviews. 8, p. 119-125 7 p.

Research output: Contribution to journalArticle

Cationic lipids destabilize lysosomal membrane in vitro

Wattiaux, R., Jadot, M., Warnier-Pirotte, M. T. & Wattiaux-De Coninck, S. 10 Nov 1997 In : FEBS Letters. 417, 2, p. 199-202 4 p.

Research output: Contribution to journalArticle

Lipids
Membranes
In Vitro Techniques
Enzymes
1,2-dioleoyloxy-3-(trimethylammonium)propane

Supramolecular assemblies from lysosomal matrix proteins and complex lipids

Jadot, M., Dubois, F., Wattiaux-De Coninck, S. & Wattiaux, R. 19 Nov 1997 In : European Journal of Biochemistry . 249, 3, p. 862-869 8 p.

Research output: Contribution to journalArticle

Agglomeration
Lipids
Proteins
lysosomal proteins
Lysosome-Associated Membrane Glycoproteins