Projects per year
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Diplomas
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Collaborations and top research areas from the last five years
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Structure-based drug design and synthesis of selective smallmolecular- weight inhibitors of FXIIa, an attractive target from the intrinsic coagulation cascade
Traina, A. (PI), Lanners, S. (Supervisor) & Pochet, L. (CoI)
1/01/25 → 30/09/26
Project: Research
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Targeted covalent probes to interfere with homomeric proteinprotein interactions: inhibition of lactate dehydrogenase (LDH) through covalent modification of key amino acids
Garcia Llinas, X. (PI), Pochet, L. (Supervisor) & Wouters, J. (CoI)
1/10/24 → 30/09/26
Project: Research
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Acquisition of an elemental analyser for the qualitative and quantitative analysis of organic substances
Pirotte, B. (PI), Delaude, L. (CoPI), MONBALIU, J.-C. M. (CoPI), Richel, A. (CoPI) & Pochet, L. (CoPI)
1/01/24 → 31/12/25
Project: Research
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DISRUPT: Towards the Targeting of Self-Assembling Proteins in Drug Design
Frédérick, R. (PI), Wouters, J. (CoPI), Pochet, L. (CoPI) & Fillet, M. (CoPI)
1/10/21 → 30/09/26
Project: Research
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THROMBO: Enzymologic, mechanistic and pharmacological study of specific inhibitors of serine proteases implicated in hemostasis disorders
Pochet, L. (PI), Dogné, J.-M. (CoI), Masereel, B. (CoI) & ROBERT, S. (Researcher)
1/09/04 → …
Project: PHD
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Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry
Pochet, L., Dieu, M., Frédérick, R., Murray, A.-M., Kempen, I., Pirotte, B. & Masereel, B., 2003, In: Tetrahedron. 59, p. 4557-4561 5 p.Research output: Contribution to journal › Article › peer-review
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Online magnetic bead based dynamic protein affinity selection coupled to LC-MS for the screening of acetylcholine binding protein ligands
Pochet, L., Heus, F., Jonker, N., Lingeman, H., Niessen, W. M. A., Kool, J. & Smit, A. B., 15 Jun 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 20, p. 1781-1788 8 p.Research output: Contribution to journal › Article › peer-review
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Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors
Robert, S., Bertolla, C., Masereel, B., Dogné, J.-M. & Pochet, L., 2008, In: Journal of Medicinal Chemistry. 51, p. 3077-3081 5 p.Research output: Contribution to journal › Article › peer-review
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In vitro assessment of the risk of ABCB1-mediated drug–drug interaction between rivaroxaban and tacrolimus in human embryonic kidney 293 recombinant cell lines
Mahieu, G., Sennesael, A. L., Pochet, L., Haufroid, V., Van Bambeke, F., Spinewine, A. & Elens, L., Jul 2024, In: Research and Practice in Thrombosis and Haemostasis. 8, 5, 102521.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery
Davoine, C., Pochet, L. & Fillet, M., Sept 2023, In: TrAC : Trends in Analytical Chemistry. 166, p. 117161 1 p., 117161.Research output: Contribution to journal › Article › peer-review
Datasets
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CCDC 1980941: Experimental Crystal Structure Determination
Ameryckx, A. (Creator), Pochet, L. (Contributor), Wang, G. (Creator), Yildiz, E. (Creator), Saadi, B. E. (Contributor), Wouters, J. (Contributor), Van Bambeke, F. (Creator) & Frédérick, R. (Contributor), University of Namur, 15 Aug 2020
DOI: 10.5517/ccdc.csd.cc24hbbb, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc24hbbb&sid=DataCite
Dataset
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CCDC 1851262: Experimental Crystal Structure Determination
Prevost, J. R. C. (Creator), Kozlova, A. (Creator), Saadi, B. E. (Contributor), Yildiz, E. (Creator), Modaffari, S. (Contributor), Lambert, D. M. (Creator), Pochet, L. (Contributor), Wouters, J. (Contributor), Dolušić, E. (Contributor) & Frédérick, R. (Contributor), University of Namur, 5 Dec 2018
DOI: 10.5517/ccdc.csd.cc204d4q, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204d4q&sid=DataCite
Dataset
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CCDC 1980940: Experimental Crystal Structure Determination
Ameryckx, A. (Creator), Pochet, L. (Contributor), Wang, G. (Creator), Yildiz, E. (Creator), Saadi, B. E. (Contributor), Wouters, J. (Contributor), Van Bambeke, F. (Creator) & Frédérick, R. (Contributor), University of Namur, 15 Aug 2020
DOI: 10.5517/ccdc.csd.cc24hb99, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc24hb99&sid=DataCite
Dataset
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CCDC 1851263: Experimental Crystal Structure Determination
Prevost, J. R. C. (Creator), Kozlova, A. (Creator), Saadi, B. E. (Contributor), Yildiz, E. (Creator), Modaffari, S. (Contributor), Lambert, D. M. (Creator), Pochet, L. (Contributor), Wouters, J. (Contributor), Dolušić, E. (Contributor) & Frédérick, R. (Contributor), University of Namur, 5 Dec 2018
DOI: 10.5517/ccdc.csd.cc204d5r, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204d5r&sid=DataCite
Dataset
Thesis
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Conception, synthèse et évaluation biologique de coumarines en tant qu'inhibiteurs de protéases à sérine
Pochet, L. (Author), Masereel, B. (Supervisor), 2000Student thesis: Doc types › Doctor of Sciences
Press/Media
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Findings from Catholic University Louvain (UCLouvain) in Factor Xa Inhibitors Reported (In vitro assessment of the risk of ABCB1-mediated drug-drug interaction between rivaroxaban and tacrolimus in human embryonic kidney 293 recombinant cell ...)
26/08/24
1 item of Media coverage
Press/Media: Expert Comment
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Findings from University of Liege in the Area of Technology Reported (Advances In Analytical Technologies Detecting and Characterizing Noncovalent Interactions for Fragment-based Drug Discovery)
4/09/23
1 item of Media coverage
Press/Media: Expert Comment
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AVANCÉE SIGNIFICATIVE DANS LE TRAITEMENT DU CANCER
Dolusic, E., Frederick, R., Masereel, B., Wouters, J., Moineaux, L. & Pochet, L.
2/02/12
1 item of Media coverage
Press/Media: Research