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Research Output 1996 2019

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Conference contribution
2001

Synthèse et évaluation enzymatique de nouvelles coumarines en tant qu'inhibiteurs de thrombine

Pochet, L., Doucet, C., Pirotte, B., Frédérick, R., Delarge, J., Reboud-Ravaux, M. & Masereel, B., 2001, Abstract Book-XVèmes Journées Franco-Belges de Pharmacochimie. Universitaires, P. & Namur, D. (eds.). p. 60

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2004

Coumarins as inhibitors of serine proteases of the coagulation cascade

Frédérick, R., Robert, S., Charlier, C., Masereel, B. & Pochet, L., 2004, Abstract Book-XVIIIth International Symposium on Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Coumarins as serine protease inhibitors

Pochet, L., Frédérick, R., Robert, S., Rolin, S. & Masereel, B., 2004, Abstract Book-XVIIIth International Symposium on Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Étude du mode d'interaction de coumarines avec la thrombine

Frédérick, R., Charlier, C., De Ruyck, J., Dieu, M., Robert, S., Masereel, B. & Pochet, L., 2004, Abstract Book-18èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Évaluation biologique de dérivés coumariniques en tant qu'inhibiteurs de protéases à sérine de la cascade de la coagulation

Robert, S., Frédérick, R., Masereel, B. & Pochet, L., 2004, Abstract Book-18èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Nouveaux dérivés cyanoguanidines de beta-cyclodextrines

Bertolla, C., Pochet, L. & Masereel, B., 2004, Abstract Book-18ème Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Synthesis of new cyanoguanidine beta-cyclodextrin derivatives

Bertolla, C., Pochet, L. & Masereel, B., 2004, Abstract Book-12th International Cyclodextrin Symposium.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2005

Évaluation biologique de coumarines en tant qu'inhibiteurs du complexe facteur tissulaire/facteur VIIa

Robert, S., Frédérick, R., Masereel, B. & Pochet, L., 2005, Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Purification de beta-cyclodextrines monofonctionnalisées par chromatographie échangeuse ionique : étude comparative

Bertolla, C., Murray, A-M., Pochet, L. & Masereel, B., 2005, Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Structure-based design of coumarins as potent thrombin inhibitors

Frédérick, R., Robert, S., Charlier, C., De Ruyck, J., Masereel, B. & Pochet, L., 2005, Abstract Book-19èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2006

Développement d'inhibiteurs sélectifs de thrombine : optimisation du substituant en position P1

Robert, S., Frédérick, R., Masereel, B. & Pochet, L., 2006, Abstract Book-20èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Évaluation pharmacologique de la beta-cyclodextrin couplée à l'ocytocine en tant que nouveau véhicule moléculaire

Bertolla, C., Rolin, S., Pochet, L. & Masereel, B., 2006, Abstract Book - XXèmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2007

Beta-cyclodextrin coupled to oxytocine: synthesis and pharmacological evaluation of a new potential drug carrier system

Bertolla, C., Rolin, S., Pochet, L. & Masereel, B., 2007, Abstract Book-13th Belgian Forum of Pharmaceutical Sciences.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Le profil d'activité de thrombine: un puissant test de criblage ex vivo pour le développement d'agents anticoagulants

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, Abstract Book-21èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Microwave assisted medicinal chemistry: application to the synthesis of coumarins and cyclodextrins

Bertolla, C., Robert, S., Pochet, L. & Masereel, B., 2007, Abstract Book-New Drugs and Drug Candidates: Recent Achievements in Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Nouveaux senseurs chimiques à base de beta-cyclodextrines comportant un motif coumarine. Synthèse, détermination structurale et étude des variations spectroscopiques

Bertolla, C., Pochet, L. & Masereel, B., 2007, Abstract Book-21ème Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Nouvelles coumarines 3-carboxamides en tant qu'inhibiteurs de facteur XIIa

Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2007, Abstract Book-21èmes Journées Franco-Belges de Pharmacochimie.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Pharmacological evaluation of 6-chloromethyl-coumarins bearing a basic moiety in the 3-position as new anticoagulant drugs

Robert, S., Frédérick, R., Masereel, B., Dogné, J-M. & Pochet, L., 2007, Abstract Book-New Drugs and Drug Candidates: Recent Achievements in Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Thrombin activity profile: a powerful ex vivo screening test for the development of anticoagulant drugs

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, Abstract Book-XXIst Congress of the International Society on Thrombosis and Haemostasis.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Thrombin activity profile: a rapid, reliable and relevant ex vivo screening test for the development of anticoagulant drugs

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2007, Abstract Book-13th Belgian Forum of Pharmaceutical Sciences.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2008

A potential new drug delivery system for cancer therapy: biotin-labelled beta-cyclodextrin.

Bertolla, C., Robert, S., Pochet, L. & Masereel, B., 2008, Abstract book - Small Molecules, Antibodies and Natural Products: Multiple Faces of Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Design, synthesis and pharmacological evaluation of novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors.

Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2008, Abstract book - Small Molecules, Antibodies and Natural Products: Multiple Faces of Medicinal Chemistry.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2009

Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs ?

Robert, S., Ghiotto, J., Pirotte, B., David, J-L., Masereel, B., Pochet, L. & Dogné, J-M., 2009, Abstract book - Annual Meeting of Belgian Society on Thrombosis and Haemostasis.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2013
32 Downloads (Pure)

coauthor on lecture: NOVEL DEVELOPMENT IN COUMARINS AS FXIIa INHIBITORS: IMPROVEMENT OF SOLUBILITY

Bouckaert, C., Vancraeynest, C., Dolušić, E., Frédérick, R. & Pochet, L., 2013, Book of Abstracts, 27èmes Journées franco-belges de Pharmacochimie / 21èmes Conférences européennes du GP2A. Vol. OC05.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access
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Factor XIIa
Coumarins
Solubility
Hemorrhage
Serine Proteases

Design and synthesis of thiosemicarbazides as inhibitors of Arginase I, a therapeutic target for anticancer immunotherapy

Colette, C., Vancraeynest, C., Serra, S., Pochet, L. & Frédérick, R., 2013, 2013 Book of Abstracts, 27èmes Journées franco-belges de Pharmacochimie / 21èmes Conférences européennes du GP2A. p. 45

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2014

Fragment Expansion of 2,5-Dichlorophenyl to Discover New FXIIa Inhibitors

Bouckaert, C., Serra, S., Frédérick, R. & Pochet, L., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 229

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Thiosemicarbazide Derivatives as Novel Indolamine-2,3-dioxygenase (IDO) Inhibitors

Serra, S., Moineaux, L., Vancraeynest, C., Masereel, B., Pochet, L., Wouters, J. & Frédérick, R., 2014, Chemmedchem EFMC-ISMC 2014 Book of Abstracts. p. 280

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2016

Estimation of rivaroxaban plasma concentrations in the perioperative setting with or without heparin bridging: an ex vivo study using dedicated chromogenic assays

Lessire, S., Douxfils, J., Pochet, L., Dincq, A-S., Larock, A-S., Gourdin, M., Dogné, J-M., Chatelain, B. & Mullier, F., 13 May 2016, Abstracts of the 62nd Annual Meeting of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis May 25–28, 2016. p. 21 1 p. CA30

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Open Access
2018

Betrixaban: Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 5 Jul 2018, JTH - Journal of thrombosis and haemostasis: Research and Practice in thrombosis and haemostasis. Issue S1 ed. Vol. Volume 2. PB364

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Betrixaban : Impact on routine and specific coagulation assays - A practical laboratory guide

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, BJH - Belgian Journal of Hematology - Clinic: Abstracts - 33rd General Annual Meeting of the Belgian Hematology Society . p. 22 42 p. PP47

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

Betrixaban: Impact on routine and specific coagulation assays - Practical laboratory guidance

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Gheldof, D., Chatelain, B., Vancraeynest, C., Devel, P., Guldenpfennig, M., Devroye, C., Mullier, F. & Douxfils, J., 2018, International Society for Laboratory Hematology: Abstracts.

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

2019
4 Downloads (Pure)

Impact of betrixaban on chromogenic anti-Xa assays - Methodologies improvements

Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Bouvy, C., Lessire, S., Mullier, F. & Douxfils, J., 2019, (En attente de publication).

Research output: Contribution in Book/Catalog/Report/Conference proceedingConference contribution

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