Projects per year
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Projects
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Development of new compounds targeting coagulation factor XIIa using innovative microfluidic assays in the context of fragment-based drug discovery
DAVOINE, C., POCHET, L. & Fillet, M.
1/10/18 → 30/09/20
Project: Research
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Design, synthesis and evaluation of FXIIa inhibitors: toward chiral peptidomimetic amidines and guanidines
SIMON, F., LANNERS, S. & POCHET, L.
1/10/18 → 30/09/20
Project: Research
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Microscale thermophoresis for the analysis of biomolecular interactions
Frédérick, R., Sonveaux, P. & POCHET, L.
1/01/18 → 31/12/19
Project: Research
Research output
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Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry
Pochet, L., Dieu, M., Frédérick, R., Murray, A-M., Kempen, I., Pirotte, B. & Masereel, B., 2003, In: Tetrahedron. 59, p. 4557-4561 5 p.Research output: Contribution to journal › Article › peer-review
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Online magnetic bead based dynamic protein affinity selection coupled to LC-MS for the screening of acetylcholine binding protein ligands
Pochet, L., Heus, F., Jonker, N., Lingeman, H., Niessen, W. M. A., Kool, J. & Smit, A. B., 15 Jun 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 20, p. 1781-1788 8 p.Research output: Contribution to journal › Article › peer-review
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Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors
Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2008, In: Journal of Medicinal Chemistry. 51, p. 3077-3081 5 p.Research output: Contribution to journal › Article › peer-review
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Assessment of low plasma concentrations of apixaban in the periprocedural setting
Lessire, S., Dincq, A-S., Siriez, R., Pochet, L., Sennesael, A-L., Vornicu, O., Hardy, M., Deceuninck, O., Douxfils, J. & Mullier, F., 1 Aug 2020, In: International Journal of Laboratory Hematology. 42, 4, p. 394-402 9 p.Research output: Contribution to journal › Article › peer-review
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Factor XII/XIIa inhibitors: Their discovery, development, and potential indications
DAVOINE, C., BOUCKAERT, C., Fillet, M. & POCHET, L., 1 Dec 2020, In: European Journal of Medicinal Chemistry. 208, 112753.Research output: Contribution to journal › Review article › peer-review
Datasets
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CCDC 1980941: Experimental Crystal Structure Determination
Ameryckx, A. (Creator), POCHET, L. (Contributor), Wang, G. (Creator), Yildiz, E. (Creator), Saadi, B. E. (Contributor), WOUTERS, J. (Contributor), Van Bambeke, F. (Creator) & Frédérick, R. (Contributor), University of Namur, 15 Aug 2020
DOI: 10.5517/ccdc.csd.cc24hbbb, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc24hbbb&sid=DataCite
Dataset
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CCDC 1851263: Experimental Crystal Structure Determination
Prevost, J. R. C. (Creator), Kozlova, A. (Creator), Saadi, B. E. (Contributor), Yildiz, E. (Creator), Modaffari, S. (Contributor), Lambert, D. M. (Creator), POCHET, L. (Contributor), WOUTERS, J. (Contributor), Dolušić, E. (Contributor) & Frédérick, R. (Contributor), University of Namur, 5 Dec 2018
DOI: 10.5517/ccdc.csd.cc204d5r, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204d5r&sid=DataCite
Dataset
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CCDC 1851262: Experimental Crystal Structure Determination
Prevost, J. R. C. (Creator), Kozlova, A. (Creator), Saadi, B. E. (Contributor), Yildiz, E. (Creator), Modaffari, S. (Contributor), Lambert, D. M. (Creator), POCHET, L. (Contributor), WOUTERS, J. (Contributor), Dolušić, E. (Contributor) & Frédérick, R. (Contributor), University of Namur, 5 Dec 2018
DOI: 10.5517/ccdc.csd.cc204d4q, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204d4q&sid=DataCite
Dataset
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CCDC 1980940: Experimental Crystal Structure Determination
Ameryckx, A. (Creator), POCHET, L. (Contributor), Wang, G. (Creator), Yildiz, E. (Creator), Saadi, B. E. (Contributor), WOUTERS, J. (Contributor), Van Bambeke, F. (Creator) & Frédérick, R. (Contributor), University of Namur, 15 Aug 2020
DOI: 10.5517/ccdc.csd.cc24hb99, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc24hb99&sid=DataCite
Dataset
Thesis
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Conception, synthèse et évaluation biologique de coumarines en tant qu'inhibiteurs de protéases à sérine
Author: Pochet, L., 2000Supervisor: Masereel, B. (Supervisor)
Student thesis: Doc types › Doctor of Sciences
Press / Media
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AVANCÉE SIGNIFICATIVE DANS LE TRAITEMENT DU CANCER
Eduard Dolusic, Raphaël Frederick, Bernard Masereel, Johan Wouters, Laurence Moineaux & Lionel Pochet
2/02/12
1 item of Media coverage
Press/Media: Research
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AVANCÉE SIGNIFICATIVE DANS LE TRAITEMENT DU CANCER
Eduard Dolusic, Raphaël Frederick, Bernard Masereel, Johan Wouters, Laurence Moineaux & Lionel Pochet
2/02/12
1 item of Media coverage
Press/Media: Research