Projects per year
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Projects
Design, synthesis and evaluation of FXIIa inhibitors: toward chiral peptidomimetic amidines and guanidines
SIMON, F., LANNERS, S. & POCHET, L.
1/10/18 → 30/09/20
Project: Research
Development of new compounds targeting coagulation factor XIIa using innovative microfluidic assays in the context of fragment-based drug discovery
DAVOINE, C., POCHET, L. & Fillet, M.
1/10/18 → 30/09/20
Project: Research
Microscale thermophoresis for the analysis of biomolecular interactions
Frédérick, R., Sonveaux, P. & POCHET, L.
1/01/18 → 31/12/19
Project: Research
Research Output
Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry
Pochet, L., Dieu, M., Frédérick, R., Murray, A-M., Kempen, I., Pirotte, B. & Masereel, B., 2003, In : Tetrahedron. 59, p. 4557-4561 5 p.Research output: Contribution to journal › Article
Online magnetic bead based dynamic protein affinity selection coupled to LC-MS for the screening of acetylcholine binding protein ligands
Pochet, L., Heus, F., Jonker, N., Lingeman, H., Niessen, W. M. A., Kool, J. & Smit, A. B., 15 Jun 2011, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 20, p. 1781-1788 8 p.Research output: Contribution to journal › Article
Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors
Robert, S., Bertolla, C., Masereel, B., Dogné, J-M. & Pochet, L., 2008, In : Journal of Medicinal Chemistry. 51, p. 3077-3081 5 p.Research output: Contribution to journal › Article
Assessment of low plasma concentrations of apixaban in the periprocedural setting
Lessire, S., Dincq, A-S., Siriez, R., Pochet, L., Sennesael, A-L., Vornicu, O., Hardy, M., Deceuninck, O., Douxfils, J. & Mullier, F., 16 Apr 2020, In : International Journal of Laboratory Hematology.Research output: Contribution to journal › Article
Development of new methodologies for the chromogenic estimation of betrixaban concentrations in plasma
Siriez, R., Evrard, J., Dogne, J-M., Pochet, L., Bouvy, C., Lessire, S., Mullier, F. & Douxfils, J., 1 Apr 2019, In : International Journal of Laboratory Hematology. 41, 2, p. 250-261 12 p.Research output: Contribution to journal › Article
Datasets
CCDC 1851262: Experimental Crystal Structure Determination
Prevost, J. R. C. (Creator), Kozlova, A. (Creator), Saadi, B. E. (Contributor), Yildiz, E. (Creator), Modaffari, S. (Contributor), Lambert, D. M. (Creator), POCHET, L. (Contributor), WOUTERS, J. (Contributor), Dolušić, E. (Contributor) & FREDERICK, R. (Contributor), University of Namur, 5 Dec 2018
DOI: 10.5517/ccdc.csd.cc204d4q, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204d4q&sid=DataCite
Dataset
CCDC 1851263: Experimental Crystal Structure Determination
Prevost, J. R. C. (Creator), Kozlova, A. (Creator), Saadi, B. E. (Contributor), Yildiz, E. (Creator), Modaffari, S. (Contributor), Lambert, D. M. (Creator), POCHET, L. (Contributor), WOUTERS, J. (Contributor), Dolušić, E. (Creator) & FREDERICK, R. (Contributor), University of Namur, 5 Dec 2018
DOI: 10.5517/ccdc.csd.cc204d5r, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc204d5r&sid=DataCite
Dataset
Thesis
Conception, synthèse et évaluation biologique de 2-thiohydantoïnes en tant qu'inhibiteurs potentiels des cyclooxygénases
Author: Gauthier, M., 17 Dec 2004Supervisor: Masereel, B. (Supervisor), Flamion, B. (Jury), Pochet, L. (Jury), Vincent, S. (Jury), Wouters, J. (Jury), GUEIFFIER, A. (External person) (Jury) & Lambert, D. M. (External person) (Jury)
Student thesis: Doc types › Doctor of Sciences
Conception, synthèse et évaluation biologique de coumarines en tant qu'inhibiteurs de protéases à sérine
Author: Pochet, L., 2000Supervisor: Masereel, B. (Supervisor)
Student thesis: Doc types › Doctor of Sciences
Design, synthesis and evaluation of coagulation FXIIa inhibitors as potential antithrombotic agents
Author: Bouckaert, C., 16 May 2017Supervisor: Pochet, L. (Supervisor), Dogne, J. (Co-Supervisor), Lanners, S. (President), De Tullio, P. (External person) (Jury), Chatelain, C. (External person) (Jury) & TEN CATE, H. (External person) (Jury)
Student thesis: Doc types › Doctor of Biomedical and Pharmaceutical Sciences
Development & validation of pharmacological tools for the preclinical testing of anticoagulants
Author: Robert, S., 7 Apr 2011Supervisor: Pochet, L. (Supervisor), Dogne, J. (Co-Supervisor), Masereel, B. (President), Caron, N. (Jury), Chatelain, C. (External person) (Jury) & TEN CATE, H. (External person) (Jury)
Student thesis: Doc types › Doctor of Biomedical and Pharmaceutical Sciences
Press / Media
AVANCÉE SIGNIFICATIVE DANS LE TRAITEMENT DU CANCER
Eduard Dolusic, Raphaël Frederick, Bernard Masereel, Johan Wouters, Laurence Moineaux & Lionel Pochet
2/02/12
1 item of Media coverage
Press/Media: Research
AVANCÉE SIGNIFICATIVE DANS LE TRAITEMENT DU CANCER
Eduard Dolusic, Raphaël Frederick, Bernard Masereel, Johan Wouters, Laurence Moineaux & Lionel Pochet
2/02/12
1 item of Media coverage
Press/Media: Research